Hori Suya, Tachihara Motoko, Tamura Daisuke, Kobayashi Kazuyuki, Nakata Kyosuke, Kamiryo Hiroshi, Sakai Yasuhiro, Itoh Tomoo, Hirose Takanori, Nishimura Yoshihiro
Division of Respiratory Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Japan.
Department of Diagnostic Pathology, Kobe University Hospital, Japan.
Intern Med. 2017 Dec 15;56(24):3333-3339. doi: 10.2169/internalmedicine.6754-15. Epub 2017 Oct 11.
A 20-year-old Japanese woman with a history of pulmonary atresia was referred to our hospital after the detection of an abnormal mass in the right lung and mediastinal lymphadenopathy. A cytological specimen obtained by transbronchial brushing indicated that the pathological diagnosis was non-small cell lung cancer. During the follow-up period, the tumor spontaneously regressed. At four months after the diagnosis, she experienced sudden bleeding from the small intestine. The histological characteristics of the small intestine tumor were compatible with the cytological characteristics of the lung tumor. Detailed immunohistochemical analyses led to a final diagnosis of epithelial angiosarcoma of the small intestine, which might have formed metastatic lesions in the lung.
一名有肺动脉闭锁病史的20岁日本女性，在右肺发现异常肿块并伴有纵隔淋巴结肿大后被转诊至我院。经支气管刷检获取的细胞学标本显示病理诊断为非小细胞肺癌。在随访期间，肿瘤自发消退。诊断后四个月，她突然出现小肠出血。小肠肿瘤的组织学特征与肺肿瘤的细胞学特征相符。详细的免疫组化分析最终诊断为小肠上皮血管肉瘤，可能已在肺部形成转移病灶。
