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非开放性颈髓髓内脂肪瘤。

Nondysraphic cervicomedullary intramedullary lipoma.

作者信息

Meher Sujeet Kumar, Tripathy Laxmi Narayan, Jain Harsh, Basu Sunandan

机构信息

Department of Neurosurgery, Medica Institute of Neurological Diseases, Medica Superspeciality Hospital, Kolkata,West Bengal, India.

出版信息

J Craniovertebr Junction Spine. 2017 Jul-Sep;8(3):271-274. doi: 10.4103/jcvjs.JCVJS_130_16.

DOI:10.4103/jcvjs.JCVJS_130_16
PMID:29021680
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5634115/
Abstract

Spinal cord lipomas are usually associated with spinal dysraphism and is most common in lumbosacral region. Spinal intradural lipoma is a rare condition accounting for less than 1% of spinal cord tumours and is most prevalent in cervicodorsal region. Intramedullary spinal cord lipoma of cervical spine not associated with spinal dysraphism is one of the rarest lesions. They usually present insidiously with slowly progressive myelopathic deficits. We present a case of nondysraphic intramedullary spinal cord lipoma with exophytic component and intracranial extension. A 30 year male patient presented with wasting of muscles of left shoulder and left forearm with resultant weakness for last two months and myelopathic signs. Magnetic resonance imaging revealed a T1 hyperintense , T2 hypointense lesion on the dorsal aspect of cervical spinal cord with intracranial extension and exophytic component. There was no contrast enhancement, fat suppression image indicated a lipoma. The patient underwent cervical laminectomy with foramen magnum decompression with subtotal resection of intramedullary lipoma. Histopathology examination confirmed the diagnosis of lipoma. Subtotal resection of intramedullary lipoma is a reasonable and acceptable surgical option considering the benign nature of lesion and high probability of neurological deterioration due to dense adhesion between lipoma and neural tissue.

摘要

脊髓脂肪瘤通常与脊髓发育异常相关,最常见于腰骶部。脊髓硬膜内脂肪瘤是一种罕见疾病,占脊髓肿瘤的比例不到1%,最常见于颈胸段。不伴有脊髓发育异常的颈椎髓内脂肪瘤是最罕见的病变之一。它们通常隐匿起病,伴有缓慢进展的脊髓病性缺损。我们报告一例具有外生性成分和颅内延伸的非发育异常性髓内脊髓脂肪瘤病例。一名30岁男性患者在过去两个月出现左肩和左前臂肌肉萎缩并伴有无力,以及脊髓病体征。磁共振成像显示颈髓背侧有一个T1高信号、T2低信号病变,伴有颅内延伸和外生性成分。无强化表现,脂肪抑制图像提示为脂肪瘤。患者接受了颈椎椎板切除术、枕骨大孔减压术及髓内脂肪瘤次全切除术。组织病理学检查确诊为脂肪瘤。考虑到病变的良性性质以及脂肪瘤与神经组织之间紧密粘连导致神经功能恶化的高可能性,髓内脂肪瘤次全切除术是一种合理且可接受的手术选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0898/5634115/3b92e8386c3f/JCVJS-8-271-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0898/5634115/c4729172c854/JCVJS-8-271-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0898/5634115/20a76eff3edb/JCVJS-8-271-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0898/5634115/35ca5da5644b/JCVJS-8-271-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0898/5634115/3b92e8386c3f/JCVJS-8-271-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0898/5634115/c4729172c854/JCVJS-8-271-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0898/5634115/20a76eff3edb/JCVJS-8-271-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0898/5634115/35ca5da5644b/JCVJS-8-271-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0898/5634115/3b92e8386c3f/JCVJS-8-271-g004.jpg

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本文引用的文献

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Nondysraphic Intramedullary Cervical Cord Lipoma with Exophytic Component: Case Report.伴有外生性成分的非神经管闭合不全性颈髓髓内脂肪瘤:病例报告
J Neurol Surg Rep. 2015 Jul;76(1):e87-90. doi: 10.1055/s-0035-1547367. Epub 2015 May 13.
2
Nondysraphic pediatric intramedullary spinal cord lipomas: report of 5 cases.非神经管闭合不全性小儿脊髓内脂肪瘤:5例报告
J Neurosurg Pediatr. 2010 Feb;5(2):172-8. doi: 10.3171/2009.9.PEDS09238.
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Cervicobulbar intramedullary lipoma.颈延髓髓内脂肪瘤
Clin Case Rep. 2023 Apr 24;11(4):e7239. doi: 10.1002/ccr3.7239. eCollection 2023 Apr.
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Teaching NeuroImage: Lower Limb Muscle Weakness Due to Intramedullary Spinal Cord Lipoma.教学神经影像:脊髓内脂肪瘤导致的下肢肌肉无力
Neurology. 2022 Oct 18;99(16):724-725. doi: 10.1212/WNL.0000000000201167. Epub 2022 Aug 26.
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Unusual presentation of a giant thoracic spinal cord lipoma.巨大的胸段脊髓脂肪瘤的不常见表现。
Spinal Cord Ser Cases. 2022 Mar 28;8(1):35. doi: 10.1038/s41394-022-00489-8.
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Intradural Lipoma at the Craniocervical Junction Presenting with Progressing Hemiparesis: A Case Report.颅颈交界处硬脊膜内脂肪瘤伴进行性偏瘫:病例报告
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