Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing, 100081, China.
Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing, 100081, China.
Appl Microbiol Biotechnol. 2018 Jan;102(1):9-16. doi: 10.1007/s00253-017-8559-z. Epub 2017 Oct 12.
The natural products cyanogenic glycosides (CNglcs) are present in various forage plant species including Sorghum spp., Trifolium spp., and Lotus spp. The release of toxic hydrogen cyanide (HCN) from endogenous CNglcs, which is known as cyanogenesis, leads to a serious problem for animal consumption while as defensive secondary metabolites, CNglcs play multiple roles in plant development and responses to adverse environment. Therefore, it is highly important to fully uncover the molecular mechanisms of CNglc biosynthesis and regulation to manipulate the contents of CNglcs in forage plants for fine-tuning the balance between defensive responses and food safety. This review summarizes recent studies on the production, function, polymorphism, and regulation of CNglcs in forage plants, aiming to provide updated knowledge on the ways to manipulate CNglcs for further beneficial economic effects.
天然产物氰苷（CNglcs）存在于各种饲料植物物种中，包括高粱属、三叶草属和百脉根属。内源性 CNglcs 释放有毒的氢氰酸（HCN），即氰化作用，这对动物的食用造成了严重的问题，而作为防御性次生代谢物，CNglcs 在植物发育和应对不利环境方面发挥着多种作用。因此，充分揭示 CNglc 生物合成和调控的分子机制，以操纵饲料植物中 CNglc 的含量，从而精细调整防御反应和食品安全之间的平衡，具有重要意义。本综述总结了关于饲料植物中 CNglc 的产生、功能、多态性和调控的最新研究，旨在提供有关操纵 CNglc 的方法的最新知识，以进一步获得有益的经济效果。
