Snell Rosie, Langran Tim, Donyai Parastou
Reading School of Pharmacy, University of Reading, PO Box 226, Whiteknights, Reading, Berkshire, RG6 6AP, UK.
Windsor, Ascot & Maidenhead Clinical Commissioning Group, KEVII Hospital, Windsor, UK.
Int J Clin Pharm. 2017 Dec;39(6):1162-1165. doi: 10.1007/s11096-017-0538-z. Epub 2017 Oct 11.
Background Polypharmacy can decrease medication adherence and increase the incidence of adverse drug reactions and drug-drug interactions, resulting in falls, hospitalisations and other complications especially in the elderly. Medication-related problems of polypharmacy can be prevented through patient-centred medication reviews but research in this area has been completed largely without examining patients' viewpoints. Objective The aim was to investigate patient views about a clinical pharmacist-led patient-centred polypharmacy medication review service completed within 17 English GP practices with those ≥ 75 years of age and prescribed ≥ 15 medications, during 415 consultations. Method A patient feedback questionnaire was constructed and face validated with two pharmacists then posted by a Clinical Commissioning Group pharmacist to all patients who had taken part in the service. Data from returned questionnaires were analysed using descriptive statistics and qualitative patient comments were analysed using thematic analysis. Results Of the 166 patients (40% response rate) who returned a feedback questionnaire 83% found the service helpful. Medication-related concerns of 94% who had a concern beforehand were addressed, and 80% understood their medicines better after the review. Patients appreciated pharmacists' personal approach, advice and explanation. Conclusion Patients expressed broadly positive views about polypharmacy reviews by clinical pharmacists within GP practices.
背景 多重用药会降低用药依从性，增加药物不良反应和药物相互作用的发生率，导致跌倒、住院及其他并发症，尤其是在老年人中。以患者为中心的药物评估可预防多重用药相关的问题，但该领域的研究在很大程度上未考量患者的观点。目的 旨在调查≥75岁且正在服用≥15种药物的患者，对在17家英国全科医生诊所开展的、由临床药剂师主导的、以患者为中心的多重用药药物评估服务的看法，该服务共进行了415次会诊。方法 编制一份患者反馈问卷，并由两名药剂师进行表面效度验证，然后由临床委托小组的药剂师将问卷寄给所有参与该服务的患者。使用描述性统计分析回收问卷的数据，使用主题分析对定性的患者评论进行分析。结果 在166名（回复率40%）返回反馈问卷的患者中，83%认为该服务有帮助。事先有用药相关顾虑的患者中，94%的顾虑得到解决，80%的患者在评估后对其药物有了更好的理解。患者赞赏药剂师的个性化方式、建议和解释。结论 患者对全科医生诊所中临床药剂师开展的多重用药评估普遍持积极看法。
