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加速康复外科在单孔腹腔镜远端胃癌根治术中的应用

Application of Enhanced Recovery After Surgery in Single-incision Laparoscopic Distal Gastrectomy.

作者信息

Zhou Junfeng, He Qingliang, Wang Jiaxing, Liu Qicai, Wang Mi

机构信息

Departments of Gastrointestinal Surgery.

Clinical Laboratory.

出版信息

Surg Laparosc Endosc Percutan Tech. 2017 Dec;27(6):449-455. doi: 10.1097/SLE.0000000000000474.

Abstract

BACKGROUND

Recently, enhanced recovery after surgery (ERAS) was widely used in the perioperative management of gastric cancer. The study aimed to evaluate the safety and effectiveness of ERAS in single-incision laparoscopic distal gastrectomy (SIDG).

MATERIALS AND METHODS

A total of 90 patients who received laparoscopic gastric cancer resection were divided into 3 groups: group A (n=30), underwent traditional multiport laparoscopic distal gastrectomy with conventional perioperative management; group B (n=30) underwent traditional multiport laparoscopic distal gastrectomy with ERAS concept; and group C (n=30), underwent SIDG with ERAS concept. Clinical data and gut function were assessed in 3 groups.

RESULTS

There were no significant differences in terms of postoperative complication, number of resected lymph nodes and blood loss among 3 groups. However, operation time was longer (P=0.003) and treatment cost was higher (P<0.001) in group C than that in group A and B. Group C had faster recovery of bowel function (P<0.001), shorter postoperative hospital stay (P=0.002), and less postoperative complication (P=0.044) than those in group A. There were no significant differences in terms of recovery of bowel function and postoperative hospital stay between group C and B (all P>0.05). The white blood cell counts were lower than group A and B (all P<0.05) and C-reactive protein in group C were lower than group A (P<0.05) and B (P>0.05).

CONCLUSIONS

The findings suggest that SIDG with ERAS may be a feasible and safe procedure for early gastric cancer because it provides a favorable cosmetic result while not compromising postoperative complications, number of resected lymph nodes, and blood loss.

摘要

背景

近年来,术后加速康复(ERAS)在胃癌围手术期管理中得到广泛应用。本研究旨在评估ERAS在单孔腹腔镜远端胃癌切除术(SIDG)中的安全性和有效性。

材料与方法

将90例行腹腔镜胃癌切除术的患者分为3组:A组(n = 30),采用传统多孔腹腔镜远端胃癌切除术及传统围手术期管理;B组(n = 30),采用传统多孔腹腔镜远端胃癌切除术并应用ERAS理念;C组(n = 30),采用单孔腹腔镜远端胃癌切除术并应用ERAS理念。评估3组患者的临床资料和肠道功能。

结果

3组患者术后并发症、切除淋巴结数量及失血量方面差异无统计学意义。然而,C组手术时间长于A组和B组(P = 0.003),治疗费用高于A组和B组(P < 0.001)。C组肠道功能恢复更快(P < 0.001),术后住院时间短于A组(P = 0.002),术后并发症少于A组(P = 0.044)。C组与B组在肠道功能恢复和术后住院时间方面差异无统计学意义(均P > 0.05)。C组白细胞计数低于A组和B组(均P < 0.05),C组C反应蛋白低于A组(P < 0.05),与B组差异无统计学意义(P > 0.05)。

结论

研究结果表明,ERAS联合SIDG对于早期胃癌可能是一种可行且安全的手术方式,因为它在不影响术后并发症、切除淋巴结数量及失血量的情况下,具有良好的美容效果。

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