Zhou Junfeng, He Qingliang, Wang Jiaxing, Liu Qicai, Wang Mi
Departments of Gastrointestinal Surgery.
Clinical Laboratory.
Surg Laparosc Endosc Percutan Tech. 2017 Dec;27(6):449-455. doi: 10.1097/SLE.0000000000000474.
Recently, enhanced recovery after surgery (ERAS) was widely used in the perioperative management of gastric cancer. The study aimed to evaluate the safety and effectiveness of ERAS in single-incision laparoscopic distal gastrectomy (SIDG).
A total of 90 patients who received laparoscopic gastric cancer resection were divided into 3 groups: group A (n=30), underwent traditional multiport laparoscopic distal gastrectomy with conventional perioperative management; group B (n=30) underwent traditional multiport laparoscopic distal gastrectomy with ERAS concept; and group C (n=30), underwent SIDG with ERAS concept. Clinical data and gut function were assessed in 3 groups.
There were no significant differences in terms of postoperative complication, number of resected lymph nodes and blood loss among 3 groups. However, operation time was longer (P=0.003) and treatment cost was higher (P<0.001) in group C than that in group A and B. Group C had faster recovery of bowel function (P<0.001), shorter postoperative hospital stay (P=0.002), and less postoperative complication (P=0.044) than those in group A. There were no significant differences in terms of recovery of bowel function and postoperative hospital stay between group C and B (all P>0.05). The white blood cell counts were lower than group A and B (all P<0.05) and C-reactive protein in group C were lower than group A (P<0.05) and B (P>0.05).
The findings suggest that SIDG with ERAS may be a feasible and safe procedure for early gastric cancer because it provides a favorable cosmetic result while not compromising postoperative complications, number of resected lymph nodes, and blood loss.
近年来,术后加速康复(ERAS)在胃癌围手术期管理中得到广泛应用。本研究旨在评估ERAS在单孔腹腔镜远端胃癌切除术(SIDG)中的安全性和有效性。
将90例行腹腔镜胃癌切除术的患者分为3组:A组(n = 30),采用传统多孔腹腔镜远端胃癌切除术及传统围手术期管理;B组(n = 30),采用传统多孔腹腔镜远端胃癌切除术并应用ERAS理念;C组(n = 30),采用单孔腹腔镜远端胃癌切除术并应用ERAS理念。评估3组患者的临床资料和肠道功能。
3组患者术后并发症、切除淋巴结数量及失血量方面差异无统计学意义。然而,C组手术时间长于A组和B组(P = 0.003),治疗费用高于A组和B组(P < 0.001)。C组肠道功能恢复更快(P < 0.001),术后住院时间短于A组(P = 0.002),术后并发症少于A组(P = 0.044)。C组与B组在肠道功能恢复和术后住院时间方面差异无统计学意义(均P > 0.05)。C组白细胞计数低于A组和B组(均P < 0.05),C组C反应蛋白低于A组(P < 0.05),与B组差异无统计学意义(P > 0.05)。
研究结果表明,ERAS联合SIDG对于早期胃癌可能是一种可行且安全的手术方式,因为它在不影响术后并发症、切除淋巴结数量及失血量的情况下,具有良好的美容效果。