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基于雷达技术的头部血液积聚非接触式监测:一项数值研究。

Radar based technology for non-contact monitoring of accumulation of blood in the head: A numerical study.

作者信息

Oziel Moshe, Korenstein Rafi, Rubinsky Boris

机构信息

Department of Physiology and Pharmacology, Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.

Department of Mechanical Engineering, University of California at Berkeley, Berkeley, CA, United States of America.

出版信息

PLoS One. 2017 Oct 12;12(10):e0186381. doi: 10.1371/journal.pone.0186381. eCollection 2017.

Abstract

BACKGROUND

This theoretical study examines the use of radar to continuously monitor "accumulation of blood in the head" (ACBH) non-invasively and from a distance, after the location of a hematoma or hemorrhage in the brain was initially identified with conventional medical imaging. Current clinical practice is to monitor ABCH with multiple, subsequent, conventional medical imaging. The radar technology introduced in this study could provide a lower cost and safe alternative to multiple conventional medical imaging monitoring for ACBH.

MATERIALS AND METHODS

The goal of this study is to evaluate the feasibility of using radar to monitor changes in blood volume in the brain through a numerical simulation of ACBH monitoring from remote, with a directional spiral slot antennae, in 3-D models of the brain. The focus of this study is on evaluating the effect of frequencies on the antennae reading. To that end we performed the calculations for frequencies of 100 MHz, 500 MHz and 1 GHz.

RESULTS AND DISCUSSION

The analysis shows that the ACBH can be monitored with radar and the monitoring resolution improves with an increase in frequency, in the range studied. However, it also appears that when typical clinical dimensions of hematoma and hemorrhage are used, the variable ratio of blood volume radius and radar wavelength can bring the measurements into the Mie and Rayleigh regions of the radar cross section. In these regions there is an oscillatory change in signal with blood volume size. For some frequencies there is an increase in signal with an increase in volume while in others there is a decrease.

CONCLUSIONS

While radar can be used to monitor ACBH non-invasively and from a distance, the observed Mie region dependent oscillatory relation between blood volume size and wavelength requires further investigation. Classifiers, multifrequency algorithms or ultra-wide band radar are possible solutions that should be explored in the future.

摘要

背景

本理论研究探讨了在通过传统医学成像初步确定脑内血肿或出血位置后,利用雷达从远处进行无创连续监测“颅内积血”(ACBH)的情况。目前的临床实践是通过多次后续的传统医学成像来监测ACBH。本研究中引入的雷达技术可为ACBH的多次传统医学成像监测提供一种成本更低且安全的替代方案。

材料与方法

本研究的目标是通过在脑的三维模型中使用定向螺旋缝隙天线对ACBH进行远程监测的数值模拟,评估利用雷达监测脑内血容量变化的可行性。本研究的重点是评估频率对天线读数的影响。为此,我们对100 MHz、500 MHz和1 GHz的频率进行了计算。

结果与讨论

分析表明,在研究范围内,雷达可用于监测ACBH,且监测分辨率随频率增加而提高。然而,当使用血肿和出血的典型临床尺寸时,血容量半径与雷达波长的可变比率可能会使测量进入雷达截面的米氏和瑞利区域。在这些区域,信号随血容量大小呈振荡变化。对于某些频率,信号随体积增加而增加,而对于其他频率则减少。

结论

虽然雷达可用于从远处无创监测ACBH,但观察到的血容量大小与波长之间依赖米氏区域的振荡关系需要进一步研究。分类器、多频算法或超宽带雷达可能是未来应探索的解决方案。

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