使用射频单线圈检测并估计人体解剖颅骨内脑出血的血肿体积。
Detection and estimating the blood accumulation volume of brain hemorrhage in a human anatomical skull using a RF single coil.
作者信息
Oziel Moshe, Rubinsky Boris, Korenstein Rafi
机构信息
Department of Physiology and Pharmacology, Tel-Aviv University, Tel-Aviv, Israel.
Department of Mechanical Engineering, University of California, Berkeley, Berkeley, CA, USA.
出版信息
PeerJ. 2020 Dec 10;8:e10416. doi: 10.7717/peerj.10416. eCollection 2020.
OBJECTIVE
An experimental study for testing a simple robust algorithm on data derived from an electromagnetic radiation device that can detect small changes in the tissue/fluid ratio in a realistic head configuration.
METHODS
Changes in the scattering parameters (S) of an inductive coil resulting from injections of chicken blood in the 0-18 ml range into calf brain tissue in a human anatomical skull were measured over a 100-1,000 MHz frequency range.
RESULTS
An algorithm that combines amplitude and phase results was found to detect changes in the tissue/fluid ratio with 90% accuracy. An algorithm that estimated the injected blood volume was found to have a 1-4 ml average error. This demonstrates the possibility of the inductive coil-based device to possess a practical ability to detect a change in the tissue/fluid ratio in the head.
SIGNIFICANCE
This study is an important step towards the goal of building an inexpensive and safe device that can detect an early brain hemorrhagic stroke.
目的
进行一项实验研究，以测试一种简单且稳健的算法，该算法应用于源自电磁辐射设备的数据，该设备能够在逼真的头部模型中检测组织/液体比例的微小变化。
方法
在100 - 1000 MHz频率范围内，测量将0 - 18毫升范围内的鸡血注入人体解剖学颅骨内的小牛脑组织时，感应线圈散射参数（S）的变化。
结果
发现一种结合幅度和相位结果的算法能够以90%的准确率检测组织/液体比例的变化。发现一种估计注入血量的算法平均误差为1 - 4毫升。这证明了基于感应线圈的设备具备检测头部组织/液体比例变化的实际能力。
意义
本研究朝着构建一种能够检测早期脑出血性中风的廉价且安全的设备这一目标迈出了重要一步。
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