Rosenberg Arlene S
Department of Dermatology and Pathology, Case Western Reserve University School of Medicine, MetroHealth Medical Center, Cleveland, Ohio.
J Cutan Pathol. 2017 Dec;44(12):1049-1050. doi: 10.1111/cup.13041. Epub 2017 Oct 11.
While histological examination is considered by most as the gold standard for burn depth assessment, it has no practical use in the clinical setting. It has, however, been used in the research setting, as a mean for evaluating emerging techniques of depth measurement. Due to the limitations of the H&E stain, other stains have also been explored, such as lactate dehydrogenase (LDH), as presented in this issue, in "Improving the Histologic Characterization of Burn Depth." As the determination of burn depth is not a typical subject in dermatopathology, a summary of selected techniques and the possible role for the LDH stain in future research, is described herein.
虽然大多数人认为组织学检查是烧伤深度评估的金标准，但它在临床环境中并无实际用途。然而，它已被用于研究环境中，作为评估新兴深度测量技术的一种手段。由于苏木精-伊红（H&E）染色的局限性，人们也探索了其他染色方法，如本期“改善烧伤深度的组织学特征”中介绍的乳酸脱氢酶（LDH）染色。由于烧伤深度的测定并非皮肤病理学的典型课题，本文将对选定的技术以及LDH染色在未来研究中的可能作用进行总结。
