核孔蛋白在神经命运中遇见转录因子。
Nuclear Pore Protein Meets Transcription Factor in Neural Fate.
机构信息
Friedrich Miescher Institute for Biomedical Research, Maulbeerstrasse 66, 4058 Basel, Switzerland.
Friedrich Miescher Institute for Biomedical Research, Maulbeerstrasse 66, 4058 Basel, Switzerland; University of Basel, 4003 Basel, Switzerland.
出版信息
Neuron. 2017 Oct 11;96(2):259-261. doi: 10.1016/j.neuron.2017.09.059.
PMID:29024652
Abstract
How nuclear architecture contributes to transcriptional regulation in neural progenitor cells (NeuPCs) is poorly understood. A study by Toda et al. (2017) now shows that the nuclear pore protein Nup153 associates with the Sox2 transcription factor in the regulation of NeuPC maintenance and neural fate.
摘要
核架构如何影响神经祖细胞（NeuPCs）中的转录调控还知之甚少。Toda 等人的一项研究（2017 年）表明，核孔蛋白 Nup153 与 Sox2 转录因子在调控 NeuPC 维持和神经命运中相互作用。
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