Saad Ashraf Abdellah, Beshlawi Ismail, Al-Rawas Abdul Hakim, Zachariah Mathew, Nazir Hanan Fawzy, Wali Yasser
Child Health Department, Sultan Qaboos University Hospital, Muscat, Oman.
Nottingham Children's Hospital, Nottingham University Hospital Trust, Nottingham, UK.
Oman Med J. 2017 Sep;32(5):425-428. doi: 10.5001/omj.2017.79.
Parvovirus is a known culprit of transient red cell aplasia (TRCA) in children with sickle cell disease (SCD). Few reports have previously described the association between the virus and acute splenic sequestration crisis (ASSC) in the same patient. Here, we are shedding light on such a potentially serious combination by reporting two cases of siblings with SCD complicated with concurrent ASSC and TRCA and presenting a review of the relevant literature.
细小病毒是已知的导致镰状细胞病（SCD）患儿发生暂时性红细胞再生障碍（TRCA）的病原体。此前鲜有报道描述该病毒与同一患者急性脾滞留危象（ASSC）之间的关联。在此，我们报告两例患有SCD并并发ASSC和TRCA的同胞病例，并对相关文献进行综述，以揭示这种潜在的严重组合情况。
