儿童益生菌：有哪些证据？
Probiotics in Children: What Is the Evidence?
作者信息
Hojsak Iva
机构信息
Children's Hospital Zagreb, Zagreb, Croatia.
University of Zagreb, School of Medicine, Zagreb, Croatia.
出版信息
Pediatr Gastroenterol Hepatol Nutr. 2017 Sep;20(3):139-146. doi: 10.5223/pghn.2017.20.3.139. Epub 2017 Sep 26.
Abstract
The number of papers discussing probiotics increases tremendously that limits the possibility for primary care physicians and clinicians to stay updated. Therefore, the aim of this paper will be to summarize available evidence of probiotic use in well-defined clinical indications of importance for pediatricians. Based on currently available evidence certain probiotic strains ( GG [LGG] and ) have proven effect in the treatment of acute gastroenteritis and prevention of antibiotic associated diarrhea. Furthermore, LGG was proven to be effective in prevention of nosocomial diarrhea and respiratory tract infection in day care centers. In conclusion, not all probiotic strains have same efficacy for all clinical indications, therefore, only strains with proven efficacy and safety should be recommended.
摘要
讨论益生菌的论文数量急剧增加，这限制了初级保健医生和临床医生了解最新信息的可能性。因此，本文的目的是总结益生菌在对儿科医生具有重要意义的明确临床适应症中应用的现有证据。基于目前可得的证据，某些益生菌菌株（鼠李糖乳杆菌GG株[LGG]等）已被证明在治疗急性胃肠炎和预防抗生素相关性腹泻方面有效果。此外，LGG已被证明在预防日托中心的医院内腹泻和呼吸道感染方面有效。总之，并非所有益生菌菌株对所有临床适应症都有相同的疗效，因此，只应推荐具有已证实疗效和安全性的菌株。
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