Walker K A, Ridley S M, Lewis T, Harwood J L
Department of Biochemistry, University College, Cardiff, Wales, U.K.
Biochem J. 1988 Aug 15;254(1):307-10. doi: 10.1042/bj2540307.
Fluazifop is a grass-selective herbicide that appears to act by inhibiting fatty acid synthesis de novo in sensitive species. Results from four different types of experiment show that this inhibition is due to an action of fluazifop on acetyl-CoA carboxylase and not on fatty acid synthetase. The acetyl-CoA carboxylase from sensitive barley (Hordeum vulgare), but not from resistant pea (Pisum sativum), is inhibited by the R stereoisomer, a finding that agrees with the herbicidal specificity of fluazifop.
精稳杀得是一种禾本科选择性除草剂,它似乎是通过抑制敏感物种中的脂肪酸从头合成来发挥作用的。四种不同类型实验的结果表明,这种抑制作用是由于精稳杀得作用于乙酰辅酶A羧化酶,而非脂肪酸合成酶。精稳杀得的R立体异构体可抑制敏感大麦(Hordeum vulgare)的乙酰辅酶A羧化酶,但不能抑制抗性豌豆(Pisum sativum)的该酶,这一发现与精稳杀得的除草特异性相符。