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土耳其安卡拉法医学委员会在2011年至2015年期间对麻醉案件中合成大麻素类型的评估。

Assessment of types of synthetic cannabinoids in narcotic cases assessed by the Council of Forensic Medicine between 2011-2015, Ankara, Turkey.

作者信息

Göl Ersin, Çok İsmet

机构信息

Ankara Narcotic Department of the Council of Forensic Medicine, 06300 Keçiören, Ankara, Turkey.

Gazi University, Faculty of Pharmacy, Department of Toxicology, 06330, Hipodrom, Ankara, Turkey.

出版信息

Forensic Sci Int. 2017 Nov;280:124-129. doi: 10.1016/j.forsciint.2017.09.017. Epub 2017 Oct 4.

DOI:10.1016/j.forsciint.2017.09.017
PMID:29028489
Abstract

Synthetic cannabinoids mimic the effects of cannabis and are the largest and fastest growing class of newly appearing designer drugs. Reports have revealed that various types of synthetic cannabinoids are mixed with herbal substances. The present study investigated the herbal substance cases involving synthetic cannabinoids in Ankara and nearby cities in Turkey. Data were collected from the reports of synthetic cannabinoids that were analyzed between January 01, 2011 and December 31, 2015 in the Ankara Narcotic Department of the Council of Forensic Medicine at the request of the judicial authorities. In all, 4610 narcotic reports were obtained and reviewed. Among these narcotic reports during the period, 370 reports (8%) were related to synthetic cannabinoids. 28 synthetic cannabinoid compounds could be identified in herbals: 5-F-AB-PINACA, 5-F-AKB-48, 5-F-NNEI, 5-F-PB-22, AB-CHMINACA, AB-FUBINACA, AB-PINACA, ADB-CHMINACA, ADB-FUBINACA, AKB-48, AM-2201, EAM-2201, JWH-018, JWH-022, JWH-031, JWH-122, JWH-201, JWH-210, JWH-250, JWH-251, JWH-307, MAM-2201, NM-2201, PB-22, RCS-4, THJ-2201, UR-144, XLR-11. The amount of herbals was 30.72g, 329.22g, 665.89g, 4844.7g, and 5684.3g in 2011, 2012, 2013, 2014, and 2015, respectively. Generally, herbals contained more than one synthetic cannabinoids. ADB-FUBINACA was the most common synthetic cannabinoid among the herbals determined in this study, which was 3132.43g, excepting multi-synthetic cannabinoid herbals. The amount and diversity of synthetic cannabinoid compounds have increased dramatically between 2011 and 2015.

摘要

合成大麻素可模拟大麻的效果,是新出现的新型毒品中数量最多且增长最快的一类。报告显示,各类合成大麻素与草本物质混合在一起。本研究调查了土耳其安卡拉及周边城市涉及合成大麻素的草本物质案例。数据收集自应司法当局要求,于2011年1月1日至2015年12月31日期间在安卡拉法医委员会麻醉品部门分析的合成大麻素报告。总共获取并审查了4610份麻醉品报告。在此期间的这些麻醉品报告中,370份(8%)与合成大麻素有关。在草本植物中可鉴定出28种合成大麻素化合物:5-F-AB-PINACA、5-F-AKB-48、5-F-NNEI、5-F-PB-22、AB-CHMINACA、AB-FUBINACA、AB-PINACA、ADB-CHMINACA、ADB-FUBINACA、AKB-48、AM-2201、EAM-2201、JWH-018,、JWH-022、JWH-031、JWH-122、JWH-201、JWH-210、JWH-250、JWH-251、JWH-307、MAM-2201、NM-2201、PB-22、RCS-4、THJ-2201、UR-144、XLR-11。2011年、2012年、2013年、2014年和2015年草本物质的量分别为30.72克、329.22克、665.89克、4844.7克和5684.3克。一般来说,草本植物含有不止一种合成大麻素。在本研究确定的草本植物中,ADB-FUBINACA是最常见的合成大麻素,除了含有多种合成大麻素的草本植物外,其含量为3132.43克。2011年至2015年期间,合成大麻素化合物的数量和种类急剧增加。

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