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猪肠道转运功能的产后发育

Postnatal development of transport function in the pig intestine.

作者信息

Smith M W

机构信息

A.F.R.C. Institute of Animal Physiology and Genetics Research, Babraham, Cambridge, England.

出版信息

Comp Biochem Physiol A Comp Physiol. 1988;90(4):577-82. doi: 10.1016/0300-9629(88)90670-6.

Abstract
  1. In the newborn pig it appears that only prenatally produced enterocytes are capable of absorbing large amounts of protein. 2. The ability of the small intestine to transport sodium, lysine, lysine containing dipeptides and glucose declines markedly during the first week of post natal life. 3. Dexamethosone causes a doubling of the sodium dependent portion of alanine uptake. 4. EGF given between days three and six of postnatal life increases sucrase and maltase activity in the distal region of the small intestine. 5. Weaning induced problems are probably not due to direct inhibition of transport properties.
摘要
  1. 在新生仔猪中,似乎只有产前产生的肠上皮细胞能够吸收大量蛋白质。2. 出生后第一周内,小肠运输钠、赖氨酸、含赖氨酸的二肽和葡萄糖的能力显著下降。3. 地塞米松使丙氨酸摄取的钠依赖性部分增加一倍。4. 在出生后第3天至第6天之间给予表皮生长因子可增加小肠远端区域的蔗糖酶和麦芽糖酶活性。5. 断奶引发的问题可能并非由于对转运特性的直接抑制。

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