接种白喉-破伤风-百日咳三联疫苗（DTP）的新西兰儿童的抗体水平。
Antibody level of New Zealand children immunized with the triple vaccine DTP (diphtheria-tetanus-pertussis).
作者信息
Lau R C
机构信息
Immunology Research and Development Unit, National Health Institute, Wellington, New Zealand.
出版信息
Epidemiol Infect. 1988 Oct;101(2):405-10. doi: 10.1017/s0950268800054352.
Enzyme-linked immunosorbent assay (ELISA) tests were used to measure IgG antibody levels in 2638 New Zealand children who had been immunized with the triple vaccine DTP. The percentage of children immune to diphtheria decreased with age. The percentage of children immune to tetanus varied from 67.1 to 55.0%. The percentage of children with measurable antibody to pertussis increased with age. The mean percentages of children with measurable antibody or immunity to one or more DTP components were 34.2% (with 3 components), 34.4% (2 components), and 78.1% (1 component). It appears the immunization strategy for diphtheria and tetanus is satisfactory for herd immunity in New Zealand children. However, the current pertussis strategy may not be providing adequate immunity to 5-year-olds in this country.
采用酶联免疫吸附测定（ELISA）检测了2638名接种白喉-破伤风-百日咳三联疫苗（DTP）的新西兰儿童的IgG抗体水平。对白喉免疫的儿童比例随年龄增长而下降。对破伤风免疫的儿童比例在67.1%至55.0%之间变化。对百日咳有可检测抗体的儿童比例随年龄增长而增加。对一种或多种DTP成分有可检测抗体或免疫的儿童的平均比例分别为34.2%（三种成分）、34.4%（两种成分）和78.1%（一种成分）。看来，新西兰儿童白喉和破伤风的免疫策略对群体免疫是令人满意的。然而，目前的百日咳免疫策略可能无法为该国5岁儿童提供足够的免疫力。
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