Borsos A, Lampé L, Balogh A, Csoknyay J, Ditròi F, Székely P
Department of Obstetrics and Gynecology, Medical University of Debrecen, Hungary.
Int J Gynaecol Obstet. 1988 Oct;27(2):249-53. doi: 10.1016/0020-7292(88)90016-1.
The aim of the study was to determine the date of regular ovulation after the menarche to better understand the physiology of female adolescence, especially as it pertains to the use of hormonal contraception. Early morning urine samples were collected from 51 girls in the perimenarche for 9 weeks semi-annually during 2 years. Estrone- and pregnanediol-3-glucuronide values were determined. Cycles lasting 35-40 days at the onset of menses shortened to 28 days after the 23rd-25th cycle. Menses reached a 5.0-5.5 day average length at about the same time. After the 20th cycle, ovulation could be demonstrated in more than 50% of the study patients. Using a scoring system, regular ovulation could be expected on the basis of somatic data with scores of greater than 16. Hormonal contraception may be prescribed 2 years after the menarche, based on scores of greater than 16 and ovulation proven be hormonal cytology and basal body temperature.
该研究的目的是确定初潮后规律排卵的时间，以更好地了解女性青春期的生理状况，尤其是与激素避孕方法的使用相关的生理状况。在两年时间里，每半年对51名初潮前后的女孩采集9周的晨尿样本。测定雌酮和孕二醇-3-葡萄糖醛酸苷的值。月经初潮时持续35 - 40天的周期在第23 - 25个周期后缩短至28天。月经平均长度在同一时间达到5.0 - 5.5天。在第20个周期后，超过50%的研究患者可显示有排卵。使用评分系统，根据躯体数据得分大于16可预期出现规律排卵。基于得分大于16以及经激素细胞学和基础体温证实有排卵，初潮后两年可开具激素避孕处方。
