Carlson Lauren J, Shaw Natalie D
Pediatric Neuroendocrinology Group, Clinical Research Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina.
Pediatric Neuroendocrinology Group, Clinical Research Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina.
J Pediatr Adolesc Gynecol. 2019 Jun;32(3):249-253. doi: 10.1016/j.jpag.2019.02.119. Epub 2019 Feb 14.
Irregular menstrual cycles due to anovulation are well described in the first few years after menarche, but the normal developmental trajectory from anovulatory to mature ovulatory cycles during adolescence remains undefined. In this article we review the very limited understanding of this final stage of female reproductive axis development and discuss why additional research in this area is critical to the health of women.
初潮后的头几年,因无排卵导致的月经周期不规律已有充分描述,但青春期从无排卵周期到成熟排卵周期的正常发育轨迹仍不明确。在本文中,我们回顾了对女性生殖轴发育这一最后阶段的非常有限的认识,并讨论了为什么该领域的更多研究对女性健康至关重要。