Physical Education Department, Metabolism, Nutrition, and Exercise Laboratory, Londrina State University, Londrina, Brazil.
Physical Education Department, Exercise Physiology Laboratory, Faculty of Physical Education, University of Campinas, Campinas, Brazil.
J Diabetes. 2018 Apr;10(4):328-337. doi: 10.1111/1753-0407.12614. Epub 2017 Dec 11.
This study analyzed the effects of a 12-week resistance training (RT) program without dietary interventions on metabolic syndrome (MetS) components and inflammatory biomarkers in older women.
Fifty-three older women (mean [±SD] age 70.4 ± 5.7 years; mean body mass index 26.7 ± 4.0 kg/m ) were randomly assigned to a training group (TG; n = 26) that performed 12 weeks of an RT program or a control group (CG; n = 27) that did not perform any type of physical exercise over the same period. Body composition (dual energy X-ray absorptiometry), muscular strength (one-repetition maximum tests), blood pressure (BP), and blood sample measurements were performed before and after intervention.
After the 12-week period, there were significantly reductions (P < 0.05) in glucose levels (-20.4% vs -0.3%), waist circumference (-1.5% vs +2.0%), and systolic BP (-6.2% vs +0.9%), and complete normalization of MetS prevalence (18% at baseline vs. 0% after 12-weeks RT) in the TG. Moreover, C-reactive protein and tumor necrosis factor-α concentrations decreased in the TG (-28.6% and -21.6%, respectively), but increased in the CG (+34.5% and +13.3%, respectively). In addition there were positive improvements in the MetS Z-score in the TG but not CG (-21.6% vs +13.3%, respectively).
The results suggest that a 12-week RT program seems to effectively reduce MetS components and inflammatory biomarkers in older women, regardless of dietary intervention. The RT-induced adaptations in body composition and inflammatory biomarkers appear to be related to healthy adaptations in risk factors for MetS.
本研究分析了 12 周抗阻训练（RT）方案而不进行饮食干预对老年女性代谢综合征（MetS）成分和炎症生物标志物的影响。
53 名老年女性（平均[±SD]年龄 70.4±5.7 岁；平均体重指数 26.7±4.0 kg/m ）被随机分为训练组（TG；n=26）和对照组（CG；n=27）。TG 组进行 12 周的 RT 方案，CG 组在同期不进行任何类型的体育锻炼。在干预前后进行身体成分（双能 X 射线吸收法）、肌肉力量（一次重复最大测试）、血压（BP）和血液样本测量。
12 周后，TG 组的血糖水平（-20.4% vs -0.3%）、腰围（-1.5% vs +2.0%）和收缩压（-6.2% vs +0.9%）显著降低，代谢综合征的患病率完全正常化（基线时为 18%，12 周 RT 后为 0%）。此外，TG 组的 C 反应蛋白和肿瘤坏死因子-α浓度降低（分别为-28.6%和-21.6%），而 CG 组增加（分别为+34.5%和+13.3%）。此外，TG 组的代谢综合征 Z 评分有积极改善，但 CG 组没有（分别为-21.6% vs +13.3%）。
结果表明，12 周 RT 方案似乎能有效降低老年女性的 MetS 成分和炎症生物标志物，而与饮食干预无关。RT 引起的身体成分和炎症生物标志物的适应性似乎与 MetS 危险因素的健康适应性有关。
