Tomeleri Crisieli M, Ribeiro Alex S, Souza Mariana F, Schiavoni Durcelina, Schoenfeld Brad J, Venturini Danielle, Barbosa Décio S, Landucci Kamila, Sardinha Luís B, Cyrino Edilson S
Metabolism, Nutrition, and Exercise Laboratory, Londrina State University, Londrina, Brazil.
Metabolism, Nutrition, and Exercise Laboratory, Londrina State University, Londrina, Brazil; Center for Research in Health Sciences, University of Northern Parana, Londrina, Brazil.
Exp Gerontol. 2016 Nov;84:80-87. doi: 10.1016/j.exger.2016.09.005. Epub 2016 Sep 9.
The main purpose of the present study was to investigate the effect of resistance training on inflammatory levels, lipid and glycemic profile in obese older women. Thirty-eight obese older women (68.2±4.2years, and 41.0±6.2% of body fat) were randomly assigned to one of two groups: A training group (TG, n=19) that performed 8weeks of RT; or a control group (CG, n=19) that did not perform any type of exercise. The RT program consisted of 8 whole-body exercises for 3 sets of 10-15 repetition maximum (RM) carried out 3 times a week. Anthropometric, body composition (DXA), muscular strength (1RM), and blood sample measurements were performed pre- and post-training. After the intervention period, the TG demonstrated significantly (P<0.05) lower values than CG for interleukin-6 (TG=3.3±1.2pg/mL vs. CG=3.8±1.4pg/mL), tumor necrosis factor alpha (TG=3.1±1.5pg/mL vs. CG=3.5±1.8pg/mL), C-reactive protein (TG=1.8±1.4mg/L vs. CG=3.2±1.8mg/L), low-density lipoprotein (TG=85.1±11.0mg/dL vs. CG=148.7±0.1mg/dL), glucose (TG=90.8±11.1mg/dL vs. CG=97.9±6.9mg/dL), trunk fat (TG=12.7±3.5kg vs. CG=14.1±4.3kg), and total body fat (TG=37.5±5.7% vs. CG=43.1±5.6%). Furthermore, TG presented significantly (P<0.05) higher values for high-density lipoprotein (TG=58.3±15.4mg/dL vs. CG=55.2±11.8mg/dL). These results suggest that 8weeks of RT promote improvements on inflammatory levels, and the lipid and glycemic profile in obese older women. These findings further support the important role of RT in healthy aging.
本研究的主要目的是调查抗阻训练对肥胖老年女性炎症水平、脂质和血糖状况的影响。38名肥胖老年女性（年龄68.2±4.2岁，体脂率41.0±6.2%）被随机分为两组：一组为训练组（TG，n = 19），进行为期8周的抗阻训练；另一组为对照组（CG，n = 19），不进行任何形式的运动。抗阻训练计划包括8项全身运动，每组进行3组，每组重复10 - 15次最大重复次数（RM），每周进行3次。在训练前后进行人体测量、身体成分（双能X线吸收法）、肌肉力量（1RM）和血样检测。干预期结束后，训练组的白细胞介素-6（TG = 3.3±1.2pg/mL，CG = 3.8±1.4pg/mL）、肿瘤坏死因子α（TG = 3.1±1.5pg/mL，CG = 3.5±1.8pg/mL）、C反应蛋白（TG = 1.8±1.4mg/L，CG = 3.2±1.8mg/L）、低密度脂蛋白（TG = 85.1±11.0mg/dL，CG = 148.7±0.1mg/dL）、血糖（TG = 90.8±11.1mg/dL , CG = 97.9±6.9mg/dL）、躯干脂肪（TG = 12.7±3.5kg，CG = 14.1±4.3kg）和全身脂肪（TG = 37.5±5.7%，CG = 43.1±5.6%）的值均显著低于对照组（P<0.05）。此外，训练组的高密度脂蛋白值显著高于对照组（P<0.05）（TG = 58.3±15.4mg/dL，CG = 55.2±11.8mg/dL）。这些结果表明，8周的抗阻训练可改善肥胖老年女性的炎症水平以及脂质和血糖状况。这些发现进一步支持了抗阻训练在健康老龄化中的重要作用。
