Ofori Emmanuel, Ona Mel, Ramai Daryl, Huang Tiangui, Xiao Philip, Reddy Madhavi
Department of Gastroenterology and Hepatology, The Brooklyn Hospital Center, Academic Affiliate of The Icahn School of Medicine at Mount Sinai, Clinical Affiliate of The Mount Sinai Hospital, Brooklyn, New York, USA.
Department of Anatomical Sciences, St. George's University School of Medicine, True Blue, Grenada.
Case Rep Gastroenterol. 2017 Aug 8;11(2):434-439. doi: 10.1159/000477716. eCollection 2017 May-Aug.
Ganglioneuromas are very rare clinical entities, and their occurrence in the large bowel lays further emphasis on their rarity. Ganglioneuromas are benign tumors of undifferentiated neural crest cells. Their clinical presentation is mostly asymptomatic, and if any symptoms are present at all, they are usually nonspecific, with excellent prognosis. We report an asymptomatic, 65-year-old male with a solitary ascending colonic polyp found on screening colonoscopy. Histology revealed benign polypoid spindle-cell proliferation as well as S100 reactivity, consistent with ganglioneuroma. We report on the clinical presentation and discuss the origin, epidemiology, treatment, and management of this lesion.
神经节神经瘤是非常罕见的临床实体，它们在大肠中的出现进一步凸显了其罕见性。神经节神经瘤是未分化神经嵴细胞的良性肿瘤。其临床表现大多无症状，若有症状，通常也不具特异性，预后良好。我们报告一例65岁无症状男性，在结肠镜筛查时发现一个孤立的升结肠息肉。组织学检查显示为良性息肉样梭形细胞增生以及S100反应阳性，符合神经节神经瘤。我们报告该病例的临床表现，并讨论此病变的起源、流行病学、治疗及管理。
