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采用包括血管内夹闭、血管内修复和开放腹部减压的综合管理方法改善破裂腹主动脉瘤的治疗效果。

Improved Outcomes for Ruptured Abdominal Aortic Aneurysms Using Integrated Management Involving Endovascular Clamping, Endovascular Replacement, and Open Abdominal Decompression.

作者信息

Aoki Chikashi, Kondo Norihiro, Saito Yoshiaki, Taniguchi Satoshi, Fukuda Wakako, Daitoku Kazuyuki, Fukuda Ikuo

机构信息

Department of Thoracic and Cardiovascular Surgery, Hirosaki University Graduate School of Medicine, Hirosaki, Aomori, Japan.

出版信息

Ann Vasc Dis. 2017 Mar 24;10(1):22-28. doi: 10.3400/avd.oa.16-00110. Epub 2017 Mar 31.

DOI:10.3400/avd.oa.16-00110
PMID:29034016
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5579800/
Abstract

Endovascular repair has become the treatment of choice for ruptured abdominal aortic aneurysms (RAAAs). To improve surgical outcomes, preoperative management is important. In 2011, we introduced integrated management, which involves endovascular aneurysm repair, stabilization of hemodynamics by endovascular clamping, and open abdominal decompression to address abdominal compartment syndrome (ACS). To evaluate the efficacy of this management strategy, 62 patients who had undergone emergency surgery for an RAAA were analyzed retrospectively: group A (n=39), where an old strategy was used, and group B (n=23), where integrated management was introduced. Patient characteristics and 30-day mortality rates were compared between the two groups. The average patient age was 67.7 years and 74.7 years for groups A and B, respectively (P=0.032). Group B patients required more frequent use of vasopressors (P=0.035). Other patient characteristics did not differ between the two groups. The duration of surgery was significantly shorter in group B than in group A (P=0.001). The total amount of transfused blood did not differ between the two groups. No patients showed symptoms of ACS. Early mortality rates were 12.8% and 8.7% in groups A and B, respectively. The number of wound infections was significantly fewer in group B than in group A. Although group B patients were significantly older and had a higher rate of vasopressor use, early mortality was improved in both groups. Morbidity was significantly better in group B with respect to the duration of surgery and number of wound infections than in group A.

摘要

血管腔内修复术已成为破裂性腹主动脉瘤(RAAA)的首选治疗方法。为改善手术效果,术前管理至关重要。2011年,我们引入了综合管理,包括血管腔内动脉瘤修复、通过血管腔内钳夹稳定血流动力学以及开腹减压以处理腹腔间隔室综合征(ACS)。为评估该管理策略的疗效,我们回顾性分析了62例接受RAAA急诊手术的患者:A组(n = 39)采用旧策略,B组(n = 23)引入综合管理。比较了两组患者的特征和30天死亡率。A组和B组患者的平均年龄分别为67.7岁和74.7岁(P = 0.032)。B组患者更频繁地使用血管升压药(P = 0.035)。两组的其他患者特征无差异。B组的手术时间明显短于A组(P = 0.001)。两组的输血量无差异。没有患者出现ACS症状。A组和B组的早期死亡率分别为12.8%和8.7%。B组的伤口感染数量明显少于A组。尽管B组患者年龄明显更大且血管升压药使用率更高,但两组的早期死亡率均有所改善。B组在手术时间和伤口感染数量方面的发病率明显优于A组。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/82e4/5579800/acdfa589a72d/avd-10-1-oa.16-00110-figure01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/82e4/5579800/acdfa589a72d/avd-10-1-oa.16-00110-figure01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/82e4/5579800/acdfa589a72d/avd-10-1-oa.16-00110-figure01.jpg

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