Kontopodis Nikolaos, Tzirakis Konstantinos, Ioannou Christos V
Vascular Surgery Unit, Department of Cardiothoracic and Vascular Surgery, University Hospital of Heraklion, University of Crete Medical School, Heraklion, Crete, Greece.
Biomechanics Laboratory, Department of Mechanical Engineering, Technological Educational Institute of Crete, Estavromenos, Heraklion, Crete, Greece.
Ann Vasc Dis. 2018 Mar 25;11(1):78-83. doi: 10.3400/avd.ra.17-00115.
Although the therapeutic management of abdominal aortic aneurysms (AAAs) is currently based on the maximum diameter criterion, this has often proved inaccurate and misleading. Conversely, the biomechanical approach, which takes into account the pressure-induced wall stress exerted at every point throughout the aneurysmal surface, has been proven superior in predicting the rupture risk of AAAs, and its value is being increasingly recognized among physicians. More recently, hemodynamic indices, such as flow-induced wall shear stresses, have been indicated as potentially significant determinants of AAA natural history. Ultimately, a statistical model that takes into account all these factors may be relevant for making a sound prediction of the rupture risk of aneurysms and optimizing the management of these patients.
尽管目前腹主动脉瘤（AAA）的治疗管理是基于最大直径标准，但这常常被证明是不准确和具有误导性的。相反，生物力学方法考虑了在整个动脉瘤表面每个点上由压力引起的壁应力，已被证明在预测AAA破裂风险方面更具优势，其价值在医生中越来越受到认可。最近，诸如血流诱导的壁面剪应力等血流动力学指标已被指出可能是AAA自然病程的重要决定因素。最终，一个考虑所有这些因素的统计模型可能对于合理预测动脉瘤破裂风险和优化这些患者的管理具有重要意义。
