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经10天抗生素治疗后确诊的由胎儿弯曲杆菌引起的肾下腹主动脉霉菌性动脉瘤

Mycotic Aneurysm of the Infrarenal Abdominal Aorta Caused by Campylobacter fetus Identified After 10-Day Antibiotic Therapy.

作者信息

Hashimoto Takehiro, Hioki Yoshihide, Komiya Kosaku, Hiramatsu Kazufumi

机构信息

Infection Control, Oita University Hospital, Yufu, JPN.

Respiratory Medicine and Infectious Diseases, Oita University Faculty of Medicine, Yufu, JPN.

出版信息

Cureus. 2025 Jun 8;17(6):e85579. doi: 10.7759/cureus.85579. eCollection 2025 Jun.

Abstract

We report a rare case of a mycotic aneurysm caused by , undetectable by Gram staining or surgical specimen culture obtained after 10 days of antimicrobial therapy. However, the pathogen was successfully detected by 16S rRNA gene sequencing. An 83-year-old woman with comorbid hypertension presented with lumbar and lateral abdominal pain and was diagnosed with an abdominal mycotic aneurysm. Despite its low sensitivity for a negative Gram staining test and culture-negative specimens, 16S rRNA gene sequencing can identify the causative organism and facilitate appropriate antibiotic therapy.

摘要

我们报告了一例罕见的霉菌性动脉瘤病例,该病例由[未提及具体病因]引起,在抗菌治疗10天后进行的革兰氏染色或手术标本培养均未检测到病原体。然而,通过16S rRNA基因测序成功检测到了病原体。一名患有高血压合并症的83岁女性出现腰腹部疼痛,被诊断为腹部霉菌性动脉瘤。尽管革兰氏染色阴性试验和培养阴性标本的敏感性较低,但16S rRNA基因测序可以识别致病微生物并有助于进行适当的抗生素治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3503/12238730/70a4c6e08a80/cureus-0017-00000085579-i01.jpg

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