van Giesen Lena, Garrity Paul A
National Center for Behavioral Genomics and Volen Center for Complex Systems Department of Biology, Brandeis University, Waltham, Massachusetts, USA.
F1000Res. 2017 Sep 26;6:1753. doi: 10.12688/f1000research.12013.1. eCollection 2017.
The ionotropic receptors (IRs) are a branch of the ionotropic glutamate receptor family and serve as important mediators of sensory transduction in invertebrates. Recent work shows that, though initially studied as olfactory receptors, the IRs also mediate the detection of taste, temperature, and humidity. Here, we summarize recent insights into IR evolution and its potential ecological significance as well as recent advances in our understanding of how IRs contribute to diverse sensory modalities.
离子型受体（IRs）是离子型谷氨酸受体家族的一个分支，是无脊椎动物感觉转导的重要介质。最近的研究表明，尽管IRs最初被作为嗅觉受体进行研究，但它们也介导味觉、温度和湿度的感知。在这里，我们总结了关于IRs进化及其潜在生态意义的最新见解，以及我们对IRs如何促成多种感觉方式理解的最新进展。
