Bjerklund Johansen T E
Department of Surgery, University of Oslo, Akershus Central Hospital, Nordbyhagen, Norway.
Scand J Urol Nephrol. 1988;22(3):165-70. doi: 10.1080/00365599.1988.11690406.
Most of the reported anomalies in undescended male gonads involve disruption of continuity in the proximal reproductive tract. In order to study the effect of this anomaly on the testis, an experimental model was developed. 16-day-old Sprague-Dawley rats were operated on. The testes were mobilized through a midline abdominal incision and further dissection was carried out under an operation microscope with 20X magnification. The efferent ducts were dissected free, clamped with a microclip, severed and ligated. The epididymis and testis were separated to the level of the inferior epididymal artery. Following surgery 11 of 35 operated testes (31%) remained in the abdomen while three (9%) descended into the opposite hemiscrotum. One of these atrophied due to torsion. The rest descended normally as did all in the sham-operated group. No surgical complications were seen. At 30-37 days the non-union operated testes were edematous, but no tubular distension was seen. The operative procedure probably involves ligation of lymphatic vessels from the testis as well as ductuli efferentes causing an interstitial edema.
大多数已报道的隐睾异常涉及近端生殖道连续性的中断。为了研究这种异常对睾丸的影响，建立了一个实验模型。对16日龄的斯普拉格-道利大鼠进行手术。通过腹部中线切口游离睾丸，并在20倍放大的手术显微镜下进一步解剖。将输出小管游离、用微型夹钳夹闭、切断并结扎。将附睾和睾丸分离至附睾下动脉水平。手术后，35个手术睾丸中有11个（31%）仍留在腹部，3个（9%）降至对侧阴囊。其中1个因扭转而萎缩。其余的睾丸下降正常，假手术组的所有睾丸也下降正常。未见手术并发症。在30 - 37天时，未下降的手术睾丸出现水肿，但未见管腔扩张。手术操作可能涉及结扎来自睾丸的淋巴管以及输出小管，从而导致间质水肿。
