Moraga Fernando A, Osorio Jorge, Calderón-Jofré Rodrigo, Pedreros Andrés
1 Laboratorio de Fisiología, Hipoxia y Función Vascular, Departamento de Ciencias Biomédicas, Facultad de Medicina, Universidad Católica del Norte , Coquimbo, Chile .
2 Instituto de Estudios de la Salud , Universidad Arturo Prat, Iquique, Chile .
High Alt Med Biol. 2018 Mar;19(1):15-20. doi: 10.1089/ham.2017.0011. Epub 2017 Oct 16.
Moraga, Fernando A., Jorge Osorio, Rodrigo Calderón-Jofré, and Andrés Pedreros. Hemoconcentration during maximum exercise in miners with chronic intermittent exposure to hypobaric hypoxia (3800 m). High Alt Med Biol. 19:15-20, 2018.
To evaluate the effect of maximum exercise on hemoconcentration in miners with chronic intermittent hypobaric hypoxia (CIHH) at 3800 m.
Sixteen miners with CIHH at high altitude (3800 m) were subjected to maximum exercise levels on a cycle ergometer, increasing exercise load by 50 W every 3 minutes at sea level and high altitude (3800 m). During exercise, arterial oxygen saturation and heart rate were measured. Blood samples were taken at each step to measure hemoglobin concentration and hematocrit. Arterial blood oxygen content was also calculated.
At sea level, a decrease in arterial oxygen saturation to 92.1% ± 2.5% was observed at 150 W and the hematocrit, hemoglobin concentration and oxygen content were not altered. At high altitude, arterial oxygen saturation decreased, reaching 88.2% ± 4.9% at 50 W and remained constant during the entire exercise protocol. Hemoglobin concentration and hematocrit increased reaching 16.4 ± 0.9 g/dL and 48.8% ± 1.6%, respectively, at 100 W and were maintained until recovery. Arterial oxygen content was constant during exercise and increased in the recovery period.
An increase in hemoglobin concentration during exercise compensates for the decline in arterial oxygen saturation, meanwhile arterial oxygen content remains constant.
莫拉加，费尔南多·A.，豪尔赫·奥索里奥，罗德里戈·卡尔德隆 - 霍弗雷，以及安德烈斯·佩德雷罗斯。长期间歇性暴露于低压低氧环境（海拔3800米）的矿工在最大运动时的血液浓缩情况。《高海拔医学与生物学》。2018年第19卷，第15 - 20页。
评估最大运动对海拔3800米处长期间歇性低压低氧（CIHH）矿工血液浓缩的影响。
16名处于高海拔（3800米）的CIHH矿工在自行车测力计上进行最大运动水平测试，在海平面和高海拔（3800米）时每隔3分钟将运动负荷增加50瓦。运动期间，测量动脉血氧饱和度和心率。在每个阶段采集血样以测量血红蛋白浓度和血细胞比容。还计算动脉血氧含量。
在海平面，当功率达到150瓦时，动脉血氧饱和度降至92.1%±2.5%，血细胞比容、血红蛋白浓度和氧含量未发生改变。在高海拔，动脉血氧饱和度下降，在50瓦时降至88.2%±4.9%，并在整个运动过程中保持不变。血红蛋白浓度和血细胞比容增加，在100瓦时分别达到16.4±0.9克/分升和48.8%±1.6%，并维持到恢复阶段。运动期间动脉血氧含量保持恒定，在恢复期增加。
运动期间血红蛋白浓度的增加补偿了动脉血氧饱和度的下降，同时动脉血氧含量保持恒定。
