Mojsiewicz-Pieńkowska Krystyna, Krenczkowska Dominika
Department of Physical Chemistry, Faculty of Pharmacy with Subfaculty of Laboratory Medicine, Medical University of Gdańsk, 80-416 Gdańsk, Al. Gen. Hallera 107, Poland.
Department of Physical Chemistry, Faculty of Pharmacy with Subfaculty of Laboratory Medicine, Medical University of Gdańsk, 80-416 Gdańsk, Al. Gen. Hallera 107, Poland.
Chemosphere. 2018 Jan;191:204-217. doi: 10.1016/j.chemosphere.2017.10.045. Epub 2017 Oct 9.
The purpose of this description is to review scientific literature from 1944 to 2017 as a source of information on the reasons for the increased interest in siloxanes (silicones). Not only the research area, but first, the changes in the tendency of research aims are important issues in the evaluation. On the one hand, the authors emphasize the unique properties of linear and cyclic siloxanes, providing many examples of beneficial applications, and on the other hand, there are some warnings of overcoming of the safety barrier of their presence in human environment. Analyzing the results from the SCOPUS database, it can be argued that the increased interest of scientists and government agencies particularly relates to the analysis of siloxanes in biological and environmental samples. This is caused not only by the widespread use of various siloxanes in the pharmaceutical, medical, cosmetic and food industries, but also by the direct contact of these compounds with tissues, as well as an increased access to knowledge and modern research tools that have developed the awareness of hazards. The development of research methods enables not only constant monitoring of progressively lower siloxanes concentrations in various samples, but because of the specificity of these methods, it also enables an identification of specific siloxane compounds and evaluation of their effects on humans and environment. This paper discusses the issues of the evolution of consciousness of exposure to siloxanes due to their increased synthesis and widespread use in many areas of human life, which contributes to environmental pollution.
本描述的目的是回顾1944年至2017年的科学文献，以此作为了解对硅氧烷（硅酮）兴趣增加原因的信息来源。在评估中，不仅研究领域，而且首先是研究目标趋势的变化都是重要问题。一方面，作者强调了线性和环状硅氧烷的独特性质，并提供了许多有益应用的例子；另一方面，也有一些关于它们在人类环境中存在突破安全界限的警告。通过分析SCOPUS数据库的结果，可以认为科学家和政府机构兴趣的增加尤其与生物和环境样品中硅氧烷的分析有关。这不仅是因为各种硅氧烷在制药、医疗、化妆品和食品工业中的广泛使用，还因为这些化合物与组织的直接接触，以及获取知识和现代研究工具的增加，这些都提高了对危害的认识。研究方法的发展不仅能够持续监测各种样品中逐渐降低的硅氧烷浓度，而且由于这些方法的特异性，还能够识别特定的硅氧烷化合物，并评估它们对人类和环境的影响。本文讨论了由于硅氧烷在人类生活许多领域的合成增加和广泛使用而导致的接触硅氧烷意识演变问题，这导致了环境污染。
