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青少年精神药物处方趋势:台湾一项基于全国人口的研究。

Psychotropic medications prescribing trends in adolescents: A nationwide population-based study in Taiwan.

作者信息

Tsai Chin-Yen, Yang Hsuan-Chia, Islam Mohaimenul, Hsieh Wan-Shan, Juan Shing-Hwa, Chen Jiang-Chen, Khan Hafsah Arshed Ali, Jian Wen-Shan

机构信息

Department of Pediatrics, Yuan's General Hospital, Kaohsiung, Taiwan.

College of Medicine Science and Technology, Taipei Medical University, Taipei, Taiwan.

出版信息

Int J Qual Health Care. 2017 Oct 1;29(6):861-866. doi: 10.1093/intqhc/mzx123.

Abstract

OBJECTIVE

To describe psychotropic medications prescription patterns among adolescents in Taiwan; focusing on age, gender, duration of treatments and various classes of psychotropic medications.

DESIGN

A retrospective description analysis.

SETTING

Taiwan National Health Insurance Database.

PARTICIPANTS

Twelve to seventeen years' patients treated with psychotropic medications.

INTERVENTION

None.

MAIN OUTCOME MEASURE(S): Percentage and duration of treatment with psychotropic medications during the study periods by medication classes and age groups were calculated. In addition, top three prescribed psychotropic medications were also determined.

RESULTS

A total of 3,120 patients were prescribed psychotropic drugs. The percentage of adolescent patients that received anxiolytics and antidepressants in 2002-2012 were 2.89% and 2.15%, respectively. Also, 851 patients (1.21%) were prescribed hypnotics and 638 (0.91%) were given sedatives. The prevalence rate of the prescription of psychotropic drugs increased steadily with age and females were more treated than males except antipsychotic. Among psychotropic drugs, antidepressants (mean: 8.6 times) were refilled more but antipsychotics (mean 188 days) were the long-term treatment drugs. Additionally, the trend of hospital visits fluctuated over the year while May and December showed a higher rate of visits.

CONCLUSIONS

These findings show that the prevalence of psychotropic drug prescriptions in Taiwanese adolescents is even low but increasing trends in the prescription of these medications raises some concern. As the evidence of psychotropic drug safety and effectiveness in adolescents is still inadequate; we recommend that healthcare providers should consider psychotropic drugs therapy, continuously monitor for outcomes and empower their patients to improve their knowledge, therapeutic outcomes and quality of life.

摘要

目的

描述台湾青少年精神科药物的处方模式;重点关注年龄、性别、治疗时长以及各类精神科药物。

设计

回顾性描述分析。

背景

台湾全民健康保险数据库。

参与者

接受精神科药物治疗的12至17岁患者。

干预措施

无。

主要观察指标

计算研究期间按药物类别和年龄组划分的精神科药物治疗百分比和时长。此外,还确定了处方量排名前三的精神科药物。

结果

共有3120名患者被开具精神科药物。2002年至2012年期间,接受抗焦虑药和抗抑郁药治疗的青少年患者百分比分别为2.89%和2.15%。此外,851名患者(1.21%)被开具催眠药,638名患者(0.91%)被给予镇静剂。精神科药物处方的患病率随年龄稳步上升,除抗精神病药物外,女性接受治疗的人数多于男性。在精神科药物中,抗抑郁药(平均:8.6次)的再填充次数更多,但抗精神病药物(平均188天)是长期治疗药物。此外,全年的就诊趋势波动,5月和12月的就诊率较高。

结论

这些发现表明,台湾青少年精神科药物处方的患病率仍然较低,但这些药物处方的增加趋势令人担忧。由于青少年使用精神科药物的安全性和有效性证据仍然不足;我们建议医疗保健提供者应考虑精神科药物治疗,持续监测治疗结果,并使患者有能力提高其知识水平、治疗效果和生活质量。

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