Department of Psychiatry, University of Michigan, Ann Arbor, Michigan, USA.
Institute for Healthcare Policy and Innovation, University of Michigan, Ann Arbor, Michigan, USA.
J Am Geriatr Soc. 2021 Jun;69(6):1479-1489. doi: 10.1111/jgs.17085. Epub 2021 Mar 8.
BACKGROUND/OBJECTIVES: Psychotropic and opioid medications are routinely prescribed for symptom management in hospice, but national estimates of prescribing are lacking. Changes in Medicare hospice payment in 2014 provide the first opportunity to examine psychotropic and opioid prescribing among hospice beneficiaries, and the factors associated with use of specific medication classes.
Cross-sectional analysis of a 20% sample of traditional and managed Medicare with Part D enrolled in hospice, 2014-2016.
Beneficiaries enrolled in the Medicare hospice benefit.
Medicare beneficiaries ≥65 newly enrolled in hospice between July 1, 2014 and December 31, 2016 (N = 554,022).
Prevalence of psychotropic and opioid medication prescribing by class and factors associated with prescribing.
70.3% of hospice beneficiaries were prescribed a psychotropic and 63.3% were prescribed an opioid. The most common psychotropic classes prescribed were: benzodiazepines (60.6%), antipsychotics (38.3%), antidepressants (18.4%), and antiepileptics (10.2%). Lorazepam (56.4%), morphine (52.8%), and haloperidol (28.6%) were received by the most beneficiaries. Prevalence of any psychotropic and opioid prescription was highest among beneficiaries who were female (76.7%), non-Hispanic white (76.6%), and those with cancer (78.9%). Compared to white beneficiaries, non-Hispanic black beneficiaries were less likely to receive nearly every class of medication, with significantly lower odds of receiving opioids (64.1% vs 57.9%; AOR 0.75, 95% CI 0.72-0.77) and benzodiazepines (61.6% vs 52.2%; AOR 0.66, 95% CI 0.64-0.68). Differences were seen across hospice diagnosis; those with cancer were more likely to receive opioids, benzodiazepines, and antipsychotics but less likely to receive antidepressants and antiepileptics.
Psychotropic and opioid medications are frequently prescribed in hospice. Observed variations in prescribing across race and ethnicity may reflect disparities in prescribing as well as patient preferences for care. Further work is important to understand factors driving prescribing given limited studies surrounding medication prescribing in hospice.
背景/目的:在临终关怀中,常规开具精神药物和阿片类药物来缓解症状,但缺乏全国范围内的处方开具数据。2014 年医疗保险临终关怀支付方式的变化为首次研究临终关怀患者的精神药物和阿片类药物处方开具情况以及与特定药物类别使用相关的因素提供了机会。
对 2014-2016 年参加医疗保险传统计划和含 Part D 的管理式医疗保险并登记进入临终关怀的 20%的样本进行横断面分析。
参加医疗保险临终关怀计划的受益人。
2014 年 7 月 1 日至 2016 年 12 月 31 日期间新登记进入临终关怀的年龄≥65 岁的 Medicare 受益人(N=554022)。
按类别列出的精神药物和阿片类药物处方开具率,以及与处方开具相关的因素。
70.3%的临终关怀受益人均开具了精神药物处方,63.3%的受益人均开具了阿片类药物处方。最常见的开具的精神药物类别为:苯二氮䓬类(60.6%)、抗精神病药(38.3%)、抗抑郁药(18.4%)和抗癫痫药(10.2%)。洛沙平(56.4%)、吗啡(52.8%)和氟哌啶醇(28.6%)是受益人数最多的药物。女性(76.7%)、非西班牙裔白人(76.6%)和癌症患者(78.9%)的精神药物和阿片类药物处方开具率最高。与非裔美国受益人相比,非西班牙裔黑人受益人的每种药物类别处方开具率都较低,接受阿片类药物(64.1%比 57.9%;优势比 0.75,95%置信区间 0.72-0.77)和苯二氮䓬类药物(61.6%比 52.2%;优势比 0.66,95%置信区间 0.64-0.68)的可能性显著降低。在临终关怀诊断中存在差异;癌症患者更有可能开具阿片类药物、苯二氮䓬类药物和抗精神病药,但不太可能开具抗抑郁药和抗癫痫药。
在临终关怀中经常开具精神药物和阿片类药物。种族和民族之间处方开具的差异可能反映了开具处方的差异以及患者对护理的偏好。鉴于围绕临终关怀药物处方开具的研究有限,进一步研究了解推动处方开具的因素非常重要。