Satoh Kenichi, Yasuda Hiroshi, Kawakami Hideshi, Tashiro Satoshi
Department of Environmetrics and Biometrics, Hiroshima University, Kasumi, Minami-ku, Hiroshima, Japan.
Department of Radiation Biophysics, Hiroshima University, Kasumi, Minami-ku, Hiroshima, Japan.
Radiat Prot Dosimetry. 2018 Aug 1;180(1-4):346-350. doi: 10.1093/rpd/ncx173.
According to an analysis of the Life Span Study cohort data conducted by the Radiation Effects Research Foundation in Hiroshima and Nagasaki, the sex-averaged excess relative risk (ERR) of all solid cancers was 0.42 Gy-Eq-1. On the other hand, analysis of the atomic bomb survivors (ABS) cohort data at Hiroshima University indicated the ERR value was 0.28 Gy-Eq-1 in Hiroshima. In both cases, initial radiation doses were derived from the dosimetry system DS02, in which the relative biological effectiveness (RBE) of neutrons was assumed to be a constant value of 10. To clarify the validity of the RBE, the authors investigated the possibility of different contributions of neutrons by using the ABS. Although there were no statistically significant differences among the estimated value of RBE (=65) and the ordinal value (=10), the corresponding ERR decreased by 30%, which might affect the interpretation of radiation health assessments.
根据广岛和长崎辐射效应研究基金会对寿命研究队列数据的分析，所有实体癌的性别平均超额相对风险（ERR）为0.42 Gy-Eq-1。另一方面，广岛大学对原子弹幸存者（ABS）队列数据的分析表明，广岛的ERR值为0.28 Gy-Eq-1。在这两种情况下，初始辐射剂量均来自剂量测定系统DS02，其中中子的相对生物效应（RBE）假定为恒定值10。为了阐明RBE的有效性，作者通过使用ABS研究了中子不同贡献的可能性。尽管RBE估计值（=65）与常规值（=10）之间没有统计学上的显著差异，但相应的ERR降低了30%，这可能会影响辐射健康评估的解释。
