Shannon M
Divisions of Clinical Pharmacology/Toxicology, Children's Hospital, Boston Massachusetts.
Ann Emerg Med. 1988 Nov;17(11):1243-7. doi: 10.1016/s0196-0644(88)80078-7.
Adulterants are found in all street samples of cocaine. They add an unappreciated dimension to the clinical toxicity of cocaine abuse. Identification of these adulterants is necessary to separate their effects from those of cocaine. The comprehensive toxic screen, which provides multiple modalities of drug analysis, will be a key diagnostic tool in the further investigation of these inherently toxic agents and their impact on syndromes of cocaine intoxication.
在所有街头可卡因样本中均发现有掺杂物。它们给可卡因滥用的临床毒性增添了一个未被重视的方面。识别这些掺杂物对于区分它们与可卡因的作用是必要的。提供多种药物分析方式的综合毒物筛查,将成为进一步研究这些本质上有毒的物质及其对可卡因中毒综合征影响的关键诊断工具。