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1
Flumazenil: a benzodiazepine antagonist.氟马西尼:一种苯二氮䓬类拮抗剂。
BMJ. 1988 Oct 22;297(6655):999-1000. doi: 10.1136/bmj.297.6655.999.
2
[Use of a benzodiazepine antagonist. Apropos of the international symposium on flumazenil].[苯二氮䓬拮抗剂的应用。关于氟马西尼国际研讨会]
Rev Prat. 1990 Jun 1;40(16):1495-6.
3
[Experience in the use of a benzodiazepine antagonist, flumazenil].[苯二氮䓬拮抗剂氟马西尼的使用经验]
Anesteziol Reanimatol. 1997 Sep-Oct(5):95-8.
4
Endogenous ligands of benzodiazepine binding site have inverse agonistic properties.苯二氮䓬结合位点的内源性配体具有反向激动特性。
Med Hypotheses. 2013 Dec;81(6):1075-7. doi: 10.1016/j.mehy.2013.10.006. Epub 2013 Oct 16.
5
[Antagonism of the effects of benzodiazepines using flumazenil (Ro 15-1788)].
Anasth Intensivther Notfallmed. 1988 Jun;23(3):153-8.
6
The use of flumazenil in the anxious and benzodiazepine-dependent ECT patient.氟马西尼在焦虑且依赖苯二氮䓬类药物的ECT患者中的应用。
J ECT. 1998 Mar;14(1):5-14.
7
Reduction of aggression during benzodiazepine withdrawal: effects of flumazenil.苯二氮䓬类药物戒断期间的攻击行为减少:氟马西尼的作用。
Pharmacol Biochem Behav. 2010 Aug;96(2):148-51. doi: 10.1016/j.pbb.2010.04.023. Epub 2010 May 6.
8
Conflicting evidence regarding the efficacy of ondansetron in benzodiazepine withdrawal.
J Pharmacol Exp Ther. 1993 Feb;264(2):622-30.
9
[Mixed benzodiazepine poisoning and reversal with flumazenil (Ro 15-1788)].
Rev Esp Anestesiol Reanim. 1989 Jan-Feb;36(1):48-50.
10
[Clinical evaluation of the effectiveness of flumazenil (RO 151788) after anesthesia with benzodiazepine only].[仅使用苯二氮䓬类药物麻醉后氟马西尼(RO 151788)有效性的临床评估]
Minerva Anestesiol. 1990 Sep;56(9):923-4.

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1
Flubromazolam overdose: A review of a new designer benzodiazepine and the role of flumazenil.氟溴唑仑过量:一种新型合成苯二氮䓬类药物及氟马西尼作用的综述
Ment Health Clin. 2019 May 10;9(3):133-137. doi: 10.9740/mhc.2019.05.133. eCollection 2019 May.
2
Reversal of chloral hydrate overdose with flumazenil.氟马西尼逆转水合氯醛过量中毒
BMJ. 1989 May 6;298(6682):1253. doi: 10.1136/bmj.298.6682.1253-a.

本文引用的文献

1
Use of the specific benzodiazepine antagonist, Ro 15-1788, in studies of physiological dependence on benzodiazepines.
Experientia. 1982 Jul 15;38(7):833-4. doi: 10.1007/BF01972300.
2
Pharmacokinetics of the selective benzodiazepine antagonist Ro 15-1788 in man.选择性苯二氮䓬拮抗剂Ro 15 - 1788在人体中的药代动力学
Eur J Clin Pharmacol. 1984;27(1):115-7.
3
Tolerance of healthy volunteers to intravenous administration of the benzodiazepine antagonist Ro 15-1788.健康志愿者对苯二氮䓬拮抗剂Ro 15 - 1788静脉注射的耐受性。
Eur J Clin Pharmacol. 1983;24(4):569-70. doi: 10.1007/BF00609905.
4
Ro 15-1788 antagonizes the effects of diazepam in man without affecting its bioavailability.Ro 15 - 1788可拮抗地西泮对人体的作用,且不影响其生物利用度。
Br J Anaesth. 1983 Apr;55(4):349-56. doi: 10.1093/bja/55.4.349.
5
Benzodiazepine withdrawal: an unfinished story.苯二氮䓬类药物戒断:一个未完成的故事。
Br Med J (Clin Res Ed). 1984 Apr 14;288(6424):1135-40. doi: 10.1136/bmj.288.6424.1135.
6
First clinical investigation of the benzodiazepine antagonist Ro 15-1788 in comatose patients.
Eur Neurol. 1983;22(1):7-11. doi: 10.1159/000115529.
7
Benzodiazepine antagonist (RO 15-1788) in ethanol intoxication: a pilot study.苯二氮䓬拮抗剂(RO 15 - 1788)用于乙醇中毒:一项初步研究。
Eur Neurol. 1985;24(5):352-4. doi: 10.1159/000115824.
8
Fatal familial insomnia and dysautonomia with selective degeneration of thalamic nuclei.致命性家族性失眠症与伴有丘脑核选择性变性的自主神经功能障碍。
N Engl J Med. 1986 Oct 16;315(16):997-1003. doi: 10.1056/NEJM198610163151605.
9
The effects of midazolam reversal by RO 15-1788 on cerebral perfusion pressure in patients with severe head injury.
Intensive Care Med. 1988;14(3):196-200. doi: 10.1007/BF00717986.
10
Pharmacokinetics and clinical use of flumazenil (Ro 15-1788).氟马西尼(Ro 15 - 1788)的药代动力学及临床应用
Clin Pharmacokinet. 1988 Jan;14(1):1-12. doi: 10.2165/00003088-198814010-00001.

Flumazenil: a benzodiazepine antagonist.

作者信息

Whitwam J G

机构信息

Royal Postgraduate Medical School, London.

出版信息

BMJ. 1988 Oct 22;297(6655):999-1000. doi: 10.1136/bmj.297.6655.999.

DOI:10.1136/bmj.297.6655.999
PMID:2903780
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1834756/
Abstract
摘要