Use of the specific benzodiazepine antagonist, Ro 15-1788, in studies of physiological dependence on benzodiazepines.

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作者信息

Cumin R, Bonetti E P, Scherschlicht R, Haefely W E

出版信息

Experientia. 1982 Jul 15;38(7):833-4. doi: 10.1007/BF01972300.

DOI:10.1007/BF01972300

PMID:6809488

Abstract

摘要

相似文献

Use of the specific benzodiazepine antagonist, Ro 15-1788, in studies of physiological dependence on benzodiazepines.

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The benzodiazepine antagonist, Ro 15-1788 does not decrease ethanol withdrawal convulsions in rats.苯二氮䓬拮抗剂Ro 15 - 1788不会降低大鼠的乙醇戒断惊厥。

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Effects of repeated RO 15-1788 administration in benzodiazepine-dependent baboons.

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Inhibition of adenosine accumulation by a CNS benzodiazepine antagonist (Ro 15-1788) and a peripheral benzodiazepine receptor ligand (Ro 05-4864).一种中枢苯二氮䓬拮抗剂（Ro 15 - 1788）和一种外周苯二氮䓬受体配体（Ro 05 - 4864）对腺苷积累的抑制作用。

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Precipitated withdrawal by a benzodiazepine receptor antagonist (Ro 15-1788) after 7 days of diazepam.

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A late-appearing benzodiazepine-induced hypoactivity that is not reversed by a receptor antagonist.一种迟发性苯二氮䓬类药物诱发的活动减退，受体拮抗剂不能使其逆转。

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Tolerance, cross-tolerance and dependence measured by operant responding in rats treated with triazolam via osmotic pumps.通过渗透泵给大鼠注射三唑仑后，用操作性反应测量耐受性、交叉耐受性和依赖性。

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Precipitated withdrawal in squirrel monkeys after repeated daily oral administration of alprazolam, diazepam, flunitrazepam or oxazepam.松鼠猴每日重复口服阿普唑仑、地西泮、氟硝西泮或奥沙西泮后出现戒断反应。

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Benzodiazepine antagonist Ro 15-1788: neurological and behavioral effects.苯二氮䓬拮抗剂Ro 15 - 1788：神经学和行为学效应

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Benzodiazepine overdose: are specific antagonists useful.苯二氮䓬类药物过量：特异性拮抗剂有用吗？

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A late-appearing benzodiazepine-induced hypoactivity that is not reversed by a receptor antagonist.一种迟发性苯二氮䓬类药物诱发的活动减退，受体拮抗剂不能使其逆转。

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Flumazenil: a benzodiazepine antagonist.氟马西尼：一种苯二氮䓬类拮抗剂。

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Reversal by alpha-2 agonists of diazepam withdrawal hyperactivity in rats.α-2激动剂对大鼠地西泮戒断多动的逆转作用。

Psychopharmacology (Berl). 1986;90(2):198-202. doi: 10.1007/BF00181241.

Disruption of schedule-controlled behavior by Ro 15-1788 one day after acute treatment with benzodiazepines.苯二氮卓类药物急性治疗一天后，Ro 15 - 1788对日程控制行为的干扰。

Psychopharmacology (Berl). 1986;88(3):398-400. doi: 10.1007/BF00180845.

Flumazenil. A preliminary review of its benzodiazepine antagonist properties, intrinsic activity and therapeutic use.氟马西尼。对其苯二氮䓬拮抗剂特性、内在活性及治疗用途的初步综述。

Drugs. 1988 Apr;35(4):448-67. doi: 10.2165/00003495-198835040-00004.

本文引用的文献

Electrophysiological studies on the specific benzodiazepine antagonist Ro 15-1788.特异性苯二氮䓬拮抗剂Ro 15 - 1788的电生理研究。

Naunyn Schmiedebergs Arch Pharmacol. 1981 Jul;316(4):317-25. doi: 10.1007/BF00501364.

Benzodiazepine antagonist Ro 15-1788: neurological and behavioral effects.苯二氮䓬拮抗剂Ro 15 - 1788：神经学和行为学效应

Psychopharmacology (Berl). 1982;78(1):8-18. doi: 10.1007/BF00470579.

Benzodiazepine antagonist Ro 15-1788: binding characteristics and interaction with drug-induced changes in dopamine turnover and cerebellar cGMP levels.苯二氮䓬拮抗剂Ro 15 - 1788：结合特性以及与药物诱导的多巴胺代谢变化和小脑环磷酸鸟苷水平变化的相互作用

J Neurochem. 1981 Sep;37(3):714-22. doi: 10.1111/j.1471-4159.1982.tb12546.x.

Selective antagonists of benzodiazepines.苯二氮䓬类选择性拮抗剂。

Nature. 1981 Apr 9;290(5806):514-6. doi: 10.1038/290514a0.

Pharmacology of midazolam.咪达唑仑的药理学

Arzneimittelforschung. 1981;31(12a):2180-201.

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