Tonella Rodrigo Marques, Ratti Ligia Dos Santos Roceto, Delazari Lilian Elisabete Bernardes, Junior Carlos Fontes, Da Silva Paula Lima, Herran Aline Ribeiro Da Silva, Dos Santos Faez Daniela Cristina, Saad Ivete Alonso Bredda, De Figueiredo Luciana Castilho, Moreno Rui, Dragosvac Desanka, Falcao Antonio Luis Eiras
School of Medical Sciences, Intensive Care Unit of Clinical Hospital, State University of Campinas (UNICAMP), Campinas, Sao Paulo, Brazil.
Neurological Intensive Care Unit, Sao Jose Hospital, Lisboa, Portugal.
J Clin Med Res. 2017 Nov;9(11):929-934. doi: 10.14740/jocmr3169w. Epub 2017 Oct 2.
Prolonged use of mechanical ventilation (MV) leads to weakening of the respiratory muscles, especially in patients subjected to sedation, but this effect seems to be preventable or more quickly reversible using respiratory muscle training. The aims of the study were to assess variations in respiratory and hemodinamic parameters with electronic inspiratory muscle training (EIMT) in tracheostomized patients requiring MV and to compare these variations with those in a group of patients subjected to an intermittent nebulization program (INP).
This was a pilot, prospective, randomized study of tracheostomized patients requiring MV in one intensive care unit (ICU). Twenty-one patients were randomized: 11 into the INP group and 10 into the EIMT group. Two patients were excluded in experimental group because of hemodynamic instability.
In the EIMT group, maximal inspiratory pressure (MIP) after training was significantly higher than that before (P = 0.017), there were no hemodynamic changes, and the total weaning time was shorter than in the INP group (P = 0.0192).
The EIMT device is safe, promotes an increase in MIP, and leads to a shorter ventilator weaning time than that seen in patients treated using INP.
长期使用机械通气(MV)会导致呼吸肌减弱,尤其是在接受镇静治疗的患者中,但使用呼吸肌训练似乎可以预防这种影响或使其更快逆转。本研究的目的是评估在需要MV的气管切开患者中进行电子吸气肌训练(EIMT)时呼吸和血液动力学参数的变化,并将这些变化与一组接受间歇性雾化治疗方案(INP)的患者进行比较。
这是一项在一个重症监护病房(ICU)对需要MV的气管切开患者进行的前瞻性随机对照试验。21例患者被随机分组:11例进入INP组,10例进入EIMT组。实验组有2例患者因血流动力学不稳定被排除。
在EIMT组中,训练后的最大吸气压力(MIP)显著高于训练前(P = 0.017),没有血液动力学变化,且总撤机时间比INP组短(P = 0.0192)。
EIMT设备是安全的,可促进MIP增加,并且与接受INP治疗的患者相比,其导致的呼吸机撤机时间更短。