Imaging Institute, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH, 44195, USA.
Department of Diagnostic Radiology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Abdom Radiol (NY). 2018 Feb;43(2):273-284. doi: 10.1007/s00261-017-1330-1.
Pancreatic ductal adenocarcinoma is the most common primary malignancy of the pancreas. The classic imaging features are a hypovascular mass with proximal ductal dilatation. Different pancreatic pathologies can mimic the imaging appearance of carcinoma including other tumors involving the pancreas (pancreatic neuroendocrine tumors, lymphoma, metastasis, and rare tumors like pancreatic acinar cell carcinoma and solid pseudopapillary tumors), inflammatory processes (chronic pancreatitis and autoimmune pancreatitis), and anatomic variants (annular pancreas). Differentiation between these entities can sometimes be challenging due to overlap of imaging features. The purpose of this article is to describe the common entities that can mimic pancreatic cancer on imaging with illustrative examples and to suggest features that can help in differentiation of these entities.
胰腺导管腺癌是胰腺最常见的原发性恶性肿瘤。其典型的影像学特征是乏血供肿块伴有胰管近端扩张。不同的胰腺病变可模拟癌的影像学表现,包括其他累及胰腺的肿瘤(胰腺神经内分泌肿瘤、淋巴瘤、转移瘤,以及罕见肿瘤如胰腺腺泡细胞癌和实性假乳头状瘤)、炎症过程(慢性胰腺炎和自身免疫性胰腺炎)和解剖变异(环状胰腺)。由于影像学特征的重叠,有时很难区分这些病变。本文旨在通过举例说明描述常见的可在影像学上模拟胰腺癌的实体,并提出有助于区分这些病变的特征。