Department of Radiology, University of Michigan Health Services, Ann Arbor, MI, USA.
Cancer Imaging. 2013 Sep 23;13(3):342-9. doi: 10.1102/1470-7330.2013.9012.
Several uncommon primary pancreatic tumors, inflammatory conditions, metastasis to the pancreas and peripancreatic masses can mimic the appearance of pancreatic ductal adenocarcinoma (PDA). Differentiation between these lesions and PDA can be challenging, due to the overlap in imaging features; however, familiarity with their typical imaging features and clinical presentation may be helpful in their differentiation, as in some cases, invasive diagnostic tests or unnecessary surgery can be avoided. The different pathologies that can mimic PDA include inflammatory conditions such as the various forms of pancreatitis (chronic-focal mass-forming, autoimmune and groove pancreatitis), pancreatic neuroendocrine tumors, solid pseudopapillary tumors, metastasis (solid non-lymphomatous and hematologic), congenital variants (annular pancreas), as well as peripancreatic lesions (accessory spleen, adrenal masses, duodenal masses, lymph nodes and vascular lesions), and certain rare pancreatic tumors (e.g., acinar cell tumors, solid serous tumors, hamartoma and solitary fibrous tumors). The clinical presentation and imaging features of the most commonly encountered mimics of PDA are discussed in this presentation with representative illustrations.
几种罕见的胰腺原发性肿瘤、炎症性疾病、胰腺转移和胰周肿块均可模拟胰腺导管腺癌（PDA）的表现。由于影像学特征存在重叠，这些病变与 PDA 之间的鉴别具有一定挑战性；然而，熟悉其典型的影像学特征和临床表现可能有助于进行鉴别，因为在某些情况下，可以避免进行有创性诊断性检查或不必要的手术。可模拟 PDA 的不同病理学包括炎症性疾病，如各种类型的胰腺炎（慢性局限性肿块形成型、自身免疫性和沟槽型胰腺炎）、胰腺神经内分泌肿瘤、实性假乳头状肿瘤、转移（实性非淋巴瘤和血液系统）、先天性变异（环状胰腺），以及胰周病变（副脾、肾上腺肿块、十二指肠肿块、淋巴结和血管病变），以及某些罕见的胰腺肿瘤（如腺泡细胞肿瘤、实性浆液性肿瘤、错构瘤和孤立性纤维肿瘤）。本演示文稿通过代表性图片讨论了最常见的 PDA 模拟病变的临床表现和影像学特征。
