Baird P A, Sadovnick A D
Department of Medical Genetics, University of British Columbia, Canada.
Lancet. 1988 Dec 10;2(8624):1354-6. doi: 10.1016/s0140-6736(88)90881-1.
Life expectancy for adults with Down syndrome was calculated from data for 1610 liveborn affected individuals identified in over 1,500,000 consecutive live births in British Columbia from 1908 to 1981. Survival to 68 years of age, predicted from the available data, is better than in previous estimates, but is still much poorer than for the general population: about 44.4% and 13.6% of liveborn Down syndrome individuals will survive to 60 and 68 years, respectively, compared with 86.4% and 78.4% of the general population.
根据1908年至1981年不列颠哥伦比亚省超过150万例连续活产中确定的1610名活产唐氏综合征患者的数据，计算出唐氏综合征成年人的预期寿命。根据现有数据预测，活到68岁的情况比之前的估计要好，但仍远低于普通人群：活产唐氏综合征患者中，分别约有44.4%和13.6%能活到60岁和68岁，而普通人群的这一比例分别为86.4%和78.4%。
