Division of Nephrology, University of New Mexico School of Medicine, Albuquerque, New Mexico.
Division of Nephrology, Stanford University School of Medicine, Palo Alto, California; and.
Clin J Am Soc Nephrol. 2017 Nov 7;12(11):1744-1752. doi: 10.2215/CJN.00270117. Epub 2017 Oct 17.
The use of palliative care in AKI is not well described. We sought to better understand palliative care practice patterns for hospitalized patients with AKI requiring dialysis in the United States.
DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: Using the 2012 National Inpatient Sample, we identified patients with AKI and palliative care encounters using validated International Classification of Diseases, Ninth Revision, Clinical Modification codes. We compared palliative care encounters in patients with AKI requiring dialysis, patients with AKI not requiring dialysis, and patients without AKI. We described the provision of palliative care in patients with AKI requiring dialysis and compared the frequency of palliative care encounters for patients with AKI requiring dialysis with that for patients with other illnesses with similarly poor prognoses. We used logistic regression to determine factors associated with the provision of palliative care, adjusting for demographics, hospital-level variables, and patient comorbidities.
We identified 3,031,036 patients with AKI, of whom 91,850 (3%) received dialysis. We observed significant patient- and hospital-level differences in the provision of palliative care for patients with AKI requiring dialysis; adjusted odds were 26% (95% confidence interval, 12% to 38%) lower in blacks and 23% (95% confidence interval, 3% to 39%) lower in Hispanics relative to whites. Lower provision of palliative care was observed for rural and urban nonteaching hospitals relative to urban teaching hospitals, small and medium hospitals relative to large hospitals, and hospitals in the Northeast compared with the South. After adjusting for age and sex, there was low utilization of palliative care services for patients with AKI requiring dialysis (8%)-comparable with rates of utilization by patients with other illnesses with poor prognosis, including cardiogenic shock (9%), intracranial hemorrhage (10%), and acute respiratory distress syndrome (10%).
The provision of palliative care varied widely by patient and facility characteristics. Palliative care was infrequently used in hospitalized patients with AKI requiring dialysis, despite its poor prognosis and the regular application of life-sustaining therapy.
急性肾损伤(AKI)患者的姑息治疗应用情况尚未得到充分描述。本研究旨在更好地了解美国需要透析的 AKI 住院患者姑息治疗的实践模式。
设计、设置、参与者和测量方法:利用 2012 年国家住院患者样本,我们使用经过验证的国际疾病分类、第九版临床修订代码确定 AKI 合并姑息治疗的患者。我们比较了需要透析的 AKI 患者、不需要透析的 AKI 患者和无 AKI 的患者的姑息治疗情况。我们描述了需要透析的 AKI 患者姑息治疗的开展情况,并比较了需要透析的 AKI 患者和其他预后同样较差的疾病患者的姑息治疗次数。我们使用逻辑回归确定与姑息治疗提供相关的因素,调整了人口统计学、医院级别变量和患者合并症。
我们共确定了 3031036 例 AKI 患者,其中 91850 例(3%)接受了透析。我们观察到需要透析的 AKI 患者姑息治疗的提供存在显著的患者和医院水平差异;与白人相比,黑人的调整后比值比(95%置信区间,12%至 38%)降低 26%,西班牙裔降低 23%(95%置信区间,3%至 39%)。与城市教学医院相比,农村和城市非教学医院、小医院和中等医院与大医院相比,以及与南部相比,东北部的医院提供姑息治疗的可能性较低。调整年龄和性别后,需要透析的 AKI 患者姑息治疗服务的利用率较低(8%),与预后较差的其他疾病患者的利用率相当,包括心源性休克(9%)、颅内出血(10%)和急性呼吸窘迫综合征(10%)。
姑息治疗的提供因患者和医疗机构特征而异。尽管 AKI 患者预后不良且经常应用生命支持治疗,但需要透析的 AKI 住院患者姑息治疗的应用仍较少。