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抗高血压治疗患者的依从性与血压控制之间的相关性。

Correlation between compliance in patients with anti-hypertensive therapy and blood pressure control.

作者信息

Zhang Huimin, Sun Juan, Zhang Haiyang, Zhu Yuhua, Xujie Mao Xujie Mao, Ai Fang, Tang Siyuan, Li Rong

机构信息

Xiang Ya Nursing School of Central South University, Changsha City, Hunan Province, China / School of Nursing of Xinxiang Medical University, Xinxiang City, Henan Province, China.

School of Nursing of Xinxiang Medical University, Xinxiang City, Henan Province, China.

出版信息

Pak J Pharm Sci. 2017 Jul;30(4(Suppl.)):1455-1460.

Abstract

This paper aims to understand the blood pressure control status for hypertension patients, and discuss the relationship between social support, medication compliance and blood pressure for hypertensive patients. The survey objective was the hypertensive patients in chronic disease management system in Xinxiang city. The survey was conducted as the questionnaire survey filled by objectives. Social support rating scale and medication therapy compliance questionnaire was utilized to evaluate the patients' social support and medication therapy compliance. 1095 patients in medication were investigated, the blood pressure of 66.6% investigated objectives was controlled at target levels (<140/90 mmHg), 70.0% investigated objectives have good medication therapy compliance; the overall social support score for hypertensive patients in medication was (40.01±6.54) points, the subjective support score, objective support score and support utilization degree score were respectively (24.43±4.61) points, (8.59±2.59) points and (7.00±2.06) points; Rank correlation coefficient of Spearman illustrated that the support utilization rating evaluation was apparently correlated to medication therapy compliance (rs=0.88, P<0.01); multivariate analysis proved that the protective factors for medication therapy compliance were the high support utilization rate (OR 1.62; 95%CI 1.192.05), long hypertensive duration (510 years: OR 2.01, 95%CI 1.422.73; more than 10 years: OR 1.46, 95%CI 1.011.99) and high average monthly household income (OR 2.03, 95%CI 1.452.69); Risk factor for blood pressure control were male (OR 0.61, 95% CI 0.470.79) and high hypertensive grade (OR 0.31, 95%CI 0.190.44); The protective factors for blood pressure control was good medication therapy compliance (OR 1.54, 95%CI 1.221.89), (average P<0.05). It required to build effective social support system, increase patients' social support utilization degree, emphasized the intervention on low average monthly household incomes, male higher rate, higher hypertensive degree, and further improve the medication therapy compliance and hypertensive control rate of hypertensive patients.

摘要

本文旨在了解高血压患者的血压控制状况,并探讨社会支持、用药依从性与高血压患者血压之间的关系。调查对象为新乡市慢性病管理系统中的高血压患者。调查采用目标填写问卷调查的方式进行。运用社会支持评定量表和药物治疗依从性问卷对患者的社会支持和药物治疗依从性进行评估。共调查了1095例正在服药的患者,66.6%的调查对象血压控制在目标水平(<140/90 mmHg),70.0%的调查对象药物治疗依从性良好;正在服药的高血压患者总体社会支持得分为(40.01±6.54)分,主观支持得分、客观支持得分和支持利用度得分分别为(24.43±4.61)分、(8.59±2.59)分和(7.00±2.06)分;Spearman等级相关系数表明支持利用度评分与药物治疗依从性显著相关(rs = 0.88,P<0.01);多因素分析证明,药物治疗依从性的保护因素为支持利用率高(OR 1.62;95%CI 1.192.05)、高血压病程长(510年:OR 2.01,95%CI 1.422.73;10年以上:OR 1.46,95%CI 1.011.99)和家庭月平均收入高(OR 2.03,95%CI 1.452.69);血压控制的危险因素为男性(OR 0.61,95%CI 0.470.79)和高血压分级高(OR 0.31,95%CI 0.190.44);血压控制的保护因素为良好的药物治疗依从性(OR 1.54,95%CI 1.221.89),(均P<0.05)。需建立有效的社会支持体系,提高患者的社会支持利用度,重视对家庭月平均收入低、男性比例高、高血压分级高的干预,进一步提高高血压患者的药物治疗依从性和血压控制率。

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