Department of Women, Children and Family Health Science, College of Nursing, University of Illinois at Chicago, Chicago, Illinois.
Department of Family and Community Medicine, Baylor College of Medicine, Houston, Texas, USA.
J Hypertens. 2018 Mar;36(3):608-618. doi: 10.1097/HJH.0000000000001594.
Hypertensive disorders of pregnancy (HDP) represent the most common cause of maternal-fetal morbidity and mortality. Yet, the prevalence and cost of postpartum (42-day) readmission (PPR) among HDP-complicated pregnancies in the United States remains unknown. This study provides national prevalence and cost estimates of HDP, and examine factors associated with potentially preventable PPR following HDP-complicated pregnancies.
The 2013 and 2014 Nationwide Readmissions Databases were used to investigate HDP and PPR among delivery hospitalizations to women aged 15-49 years. PPR rates, length of stay, and costs were stratified by four HDP subtypes based on timing and severity of their condition. Survey logistic regression was employed to generate adjusted odds ratios for the association between HDP and PPR.
In 2013 and 2014, there were 6.3 million delivery hospitalizations; 666 506 (10.6%) were complicated by HDP. Annually, HDP was responsible for higher rates of potentially preventable PPR. Among HDP-complicated pregnancies, the 42-day all-cause PPR rate ranged from 2.5% (gestational hypertension) to 4.6% (superimposed preeclampsia/eclampsia). Compared with normotensive pregnancies, HDP resulted in an excess 404 800 hospital days and inpatient care costs of $731 million. Even after controlling for patient-level and hospital-level confounders, all hypertensive subgroups continued to have at least two-fold, statistically significant, increased odds of potentially preventable PPR.
HDP is associated with increased risk of PPR and substantial medical costs. Preventive efforts should be made to identify women at increased risk of PPR during hospitalization so that transition care intervention can be initiated.
妊娠高血压疾病(HDP)是孕产妇和胎儿发病率和死亡率的最常见原因。然而,美国 HDP 复杂妊娠产后(42 天)再入院(PPR)的流行率和成本尚不清楚。本研究提供了美国 HDP 的全国流行率和成本估计,并研究了与 HDP 复杂妊娠后可能可预防的 PPR 相关的因素。
使用 2013 年和 2014 年全国再入院数据库,调查了年龄在 15-49 岁的产妇住院分娩中 HDP 和 PPR 的情况。根据疾病的发生时间和严重程度,将 PPR 率、住院时间和费用分为四种 HDP 亚型。采用调查逻辑回归分析 HDP 与 PPR 之间的关联。
2013 年和 2014 年,共有 630 万例分娩住院,其中 666506 例(10.6%)并发 HDP。每年,HDP 导致更高的潜在可预防 PPR 率。在 HDP 复杂妊娠中,42 天全因 PPR 率范围为 2.5%(妊娠高血压)至 4.6%(重叠子痫前期/子痫)。与血压正常的妊娠相比,HDP 导致额外的 404800 个住院日和 7.31 亿美元的住院费用。即使在控制了患者水平和医院水平的混杂因素后,所有高血压亚组仍然至少有两倍,具有统计学意义,增加了潜在可预防的 PPR 的几率。
HDP 与 PPR 风险增加和大量医疗费用相关。应在住院期间采取预防措施,识别出有 PPR 风险增加的妇女,以便启动过渡护理干预。