Palatnik Anna, Hauspurg Alisse, Hoppe Kara K, Yee Lynn M, Kulinski Jacqueline, Khan Sadiya S, Sabol Bethany, Yarrington Christina D, Freaney Priya M, Parker Samantha E
Department of Obstetrics and Gynecology, Medical College of Wisconsin, Milwaukee, Wisconsin.
Cardiovascular Center, Medical College of Wisconsin, Milwaukee, Wisconsin.
Am J Perinatol. 2024 Oct 10. doi: 10.1055/a-2416-5974.
Hypertensive disorders of pregnancy (HDPs) are a key contributor to maternal morbidity and mortality. Several gaps in knowledge remain regarding best practices in the postpartum management of HDPs. In this review, we describe postpartum HDPs management among six large academic U.S. hospital systems: Medical College of Wisconsin, University of Pittsburgh, University of Wisconsin-Madison, Northwestern University, University of Minnesota, and Boston Medical Center. We identified that all six health systems discharge patients with HDPs diagnosed with a blood pressure (BP) cuff and use the same two antihypertensive medications, nifedipine and labetalol, as first- and second-line treatment of HDPs. Northwestern University routinely adds oral furosemide for 5 days for patients with BP that exceeds 150/100 mm Hg. Most hospital systems administer magnesium sulfate routinely when readmission for HDPs occurs. In contrast, there was variation in BP threshold for antihypertensive treatment initiation, use of remote BP monitoring program, use of a transition clinic, delivery or lack of education on long-term cardiovascular disease risk, and BP management through the first 6 weeks postpartum and beyond. Based on the clinical review, we identified clinical gaps and formulated considerations for research priorities in the field of postpartum HDPs management. KEY POINTS: · Several gaps in knowledge remain regarding best practices in postpartum management of HDPs.. · There is a variation in the BP threshold for antihypertensive treatment initiation.. · Data are lacking on the reduction in severe maternal morbidity (SMM) and racial disparities in SMM with remote monitoring..
妊娠期高血压疾病(HDPs)是孕产妇发病和死亡的主要原因。关于HDPs产后管理的最佳实践仍存在一些知识空白。在本综述中,我们描述了美国六个大型学术医疗系统中HDPs的产后管理情况,这六个系统分别是:威斯康星医学院、匹兹堡大学、威斯康星大学麦迪逊分校、西北大学、明尼苏达大学和波士顿医疗中心。我们发现,所有这六个医疗系统均使用血压袖带对诊断为HDPs的患者进行出院评估,并使用硝苯地平和拉贝洛尔这两种相同的抗高血压药物作为HDPs的一线和二线治疗药物。西北大学通常会对血压超过150/100 mmHg的患者连续5天加用口服速尿。大多数医院系统在患者因HDPs再次入院时会常规使用硫酸镁。相比之下,在抗高血压治疗起始血压阈值、远程血压监测程序的使用、过渡诊所的使用、是否提供或缺乏关于长期心血管疾病风险的教育以及产后前6周及以后的血压管理方面存在差异。基于临床综述,我们确定了临床差距,并制定了产后HDPs管理领域研究重点的考量因素。要点:· 关于HDPs产后管理的最佳实践仍存在一些知识空白。· 抗高血压治疗起始血压阈值存在差异。· 缺乏关于远程监测降低严重孕产妇发病率(SMM)及SMM种族差异的数据。