Departamento de Fisioterapia, Motion in Brains Research Group, Centro Superior de Estudios Universitarios La Salle, Universidad Autónoma de Madrid, Madrid, Spain.
Respiration. 2018;95(2):87-97. doi: 10.1159/000481264. Epub 2017 Oct 19.
Exercise-based rehabilitation is already a part of cystic fibrosis (CF) treatment; however, patient adherence is low.
To assess the effectiveness of a home exercise programme using active video games (AVGs) as a training modality for children and adolescents with CF.
Thirty-nine children with CF were randomised to a control group (CG, n = 20, age 11 ± 6 years; FEV1 86.2 ± 20.5% of predicted) or a training group (AVGG, n = 19, age 13 ± 3 years; FEV1 82.7 ± 21.7% of predicted). The home training protocol consisted of 30- to 60-min sessions, 5 days/week, for 6 weeks using a Nintendo Wii™ platform. Exercise capacity was measured by the 6-min walk test (6MWT) and modified shuttle walk test (MSWT); muscular strength was estimated using the horizontal jump test (HJT), medicine ball throw (MBT), and hand grip strength (right [RHG]; left [LHG]); and quality of life was rated using the Cystic Fibrosis Questionnaire-Revised (CFQ-R). All the children were measured at baseline, after rehabilitation, and at 12 months.
For the group × time interaction ANOVAs, the AVGG showed significant between-group differences in exercise capacity: 6MWT farthest walking distance, 38.4 m (p < 0.01); MSWT farthest walking distance, 78.4 m (p < 0.05); and muscular strength: HJT 9.8 cm, MBT 30.8 cm, RHG 7 kg, and LHG 6.5 kg (p < 0.01), before versus after intervention. The CFQ-R reported significantly higher scores on respiratory symptoms after the intervention and favoured the AVGG, and there was an improvement in other domains after 12 months. Adherence to the home exercise programme was 95% during the 6- week intervention period.
A home-based programme using AVGs can effectively improve exercise capacity, muscular strength and quality of life in the short-term in children and adolescents with CF. The effects of training on muscle performance and quality of life were sustained over 12 months.
运动康复已经成为囊性纤维化（CF）治疗的一部分，但患者的依从性很低。
评估使用主动视频游戏（AVG）作为培训模式对 CF 患儿和青少年进行家庭锻炼计划的效果。
39 名 CF 患儿被随机分为对照组（CG，n = 20，年龄 11 ± 6 岁；FEV1 预测值的 86.2 ± 20.5%）或训练组（AVGG，n = 19，年龄 13 ± 3 岁；FEV1 预测值的 82.7 ± 21.7%）。家庭训练方案包括使用任天堂 Wii™平台进行 30 至 60 分钟/次，每周 5 天，共 6 周。运动能力通过 6 分钟步行测试（6MWT）和改良 shuttle 步行测试（MSWT）进行测量；肌肉力量使用水平跳跃测试（HJT）、药球投掷（MBT）和手握力（右手[RHG]；左手[LHG]）进行评估；生活质量使用囊性纤维化问卷修订版（CFQ-R）进行评估。所有患儿均在基线、康复后和 12 个月时进行测量。
对于组×时间交互方差分析，AVGG 在运动能力方面显示出显著的组间差异：6MWT 最远步行距离，38.4m（p < 0.01）；MSWT 最远步行距离，78.4m（p < 0.05）；肌肉力量：HJT 9.8cm，MBT 30.8cm，RHG 7kg，LHG 6.5kg（p < 0.01），干预前与干预后。CFQ-R 在干预后报告呼吸症状的评分显著升高，并且有利于 AVGG，并且在 12 个月后其他领域也有所改善。家庭锻炼计划的依从性在 6 周干预期间为 95%。
在家中使用 AVG 进行的计划可以在短期内有效提高 CF 患儿和青少年的运动能力、肌肉力量和生活质量。训练对肌肉性能和生活质量的影响在 12 个月后仍能持续。
