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管理 75 岁及以上患者的高血压。

Managing Hypertension in Patients Aged 75 Years and Older.

机构信息

Cardiology Division, Department of Medicine, Westchester Medical Center and New York Medical College, Macy Pavilion, Room 141, Valhalla, NY, 10595, USA.

出版信息

Curr Hypertens Rep. 2017 Oct 18;19(11):88. doi: 10.1007/s11906-017-0785-3.

DOI:10.1007/s11906-017-0785-3
PMID:29046992
Abstract

On the basis of the available data, we would diagnose a normal blood pressure in elderly persons including those 75 years of age and older if the blood pressure was below 120/80 mmHg. We would diagnose hypertension in elderly persons including those aged 75 years and older if the systolic blood pressure was 130 mmHg and higher or if the diastolic blood pressure was 80 mmHg and higher. We would treat these elderly patients with hypertension to a blood pressure goal of less than 130/80 mmHg if the blood pressure was obtained by automated blood pressure monitoring in a quiet room. We would consider treating high-risk persons aged 75 years and older to a blood pressure goal of less than 120/80 mmHg if they were carefully monitored for serious adverse events. If the blood pressure is more than 20/10 mmHg above the goal blood pressure, we would initiate antihypertensive drug therapy with two antihypertensive drugs. The initial drug of choice for the treatment of hypertension in adults aged 75 years and older should be based on co-morbidities, co-incidental indications, tolerability, and cost.

摘要

基于现有数据,如果血压低于 120/80mmHg,我们将诊断 75 岁及以上老年人的血压正常。如果 75 岁及以上老年人的收缩压为 130mmHg 及以上,或舒张压为 80mmHg 及以上,我们将诊断为老年人高血压。如果通过安静室内自动血压监测获得血压,我们将对这些老年高血压患者进行治疗,使其血压目标值低于 130/80mmHg。如果对 75 岁及以上的高危人群进行仔细监测以防止严重不良事件,我们将考虑将其血压目标值设定为低于 120/80mmHg。如果血压比目标血压高 20/10mmHg 以上,我们将开始使用两种降压药物进行降压药物治疗。治疗 75 岁及以上成年人高血压的初始药物选择应基于合并症、合并症指征、耐受性和成本。

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本文引用的文献

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Managing Hypertension in the Elderly: What is Different, What is the Same?老年高血压管理:有何不同,有何相同?
Curr Hypertens Rep. 2017 Aug;19(8):67. doi: 10.1007/s11906-017-0764-8.
2
Potential Deaths Averted and Serious Adverse Events Incurred From Adoption of the SPRINT (Systolic Blood Pressure Intervention Trial) Intensive Blood Pressure Regimen in the United States: Projections From NHANES (National Health and Nutrition Examination Survey).在美国采用收缩压干预试验(SPRINT)强化血压治疗方案避免的潜在死亡和发生的严重不良事件:来自美国国家健康与营养检查调查(NHANES)的预测
Circulation. 2017 Apr 25;135(17):1617-1628. doi: 10.1161/CIRCULATIONAHA.116.025322. Epub 2017 Feb 13.
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Are two drugs better than one? A review of combination therapies for hypertension.
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Expert Opin Pharmacother. 2017 Mar;18(4):377-386. doi: 10.1080/14656566.2017.1288719. Epub 2017 Feb 8.
4
American Diabetes Association Standards of Medical Care in Diabetes 2017.《2017年美国糖尿病协会糖尿病医疗护理标准》
J Diabetes. 2017 Apr;9(4):320-324. doi: 10.1111/1753-0407.12524.
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On-Treatment Blood Pressure and Cardiovascular Outcomes in Older Adults With Isolated Systolic Hypertension.老年单纯收缩期高血压患者治疗期间的血压与心血管结局
Hypertension. 2017 Feb;69(2):220-227. doi: 10.1161/HYPERTENSIONAHA.116.08600. Epub 2017 Jan 3.
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Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants.1975年至2015年全球血压趋势:对1479项基于人群的测量研究(涉及1910万参与者)的汇总分析。
Lancet. 2017 Jan 7;389(10064):37-55. doi: 10.1016/S0140-6736(16)31919-5. Epub 2016 Nov 16.
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Isolated Systolic Hypertension: An Update After SPRINT.单纯收缩期高血压:SPRINT 后的更新。
Am J Med. 2016 Dec;129(12):1251-1258. doi: 10.1016/j.amjmed.2016.08.032. Epub 2016 Sep 14.
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Circulation. 2016 Nov 1;134(18):1308-1310. doi: 10.1161/CIRCULATIONAHA.116.023263. Epub 2016 Sep 12.
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Comparing the SPRINT and the HOPE-3 Blood Pressure Trial.比较收缩压干预试验(SPRINT)和降压治疗预防心血管事件试验(HOPE-3)。
JAMA Cardiol. 2016 Nov 1;1(8):855-856. doi: 10.1001/jamacardio.2016.2051.
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Global Disparities of Hypertension Prevalence and Control: A Systematic Analysis of Population-Based Studies From 90 Countries.高血压患病率与控制情况的全球差异:来自90个国家基于人群研究的系统分析
Circulation. 2016 Aug 9;134(6):441-50. doi: 10.1161/CIRCULATIONAHA.115.018912.