Yamamoto K, Hasobe M, Saneyoshi M
Department of Virology and Rickettsiology, National Institute of Health, Tokyo, Japan.
Acta Virol. 1988 Sep;32(5):386-92.
Four sulphur-containing purine nucleoside analogues: 6MP, 6-thioinosine, 6-methylthioinosine and 6-ethylthioinosine, were examined for antiviral activity against some RNA viruses. All compounds extensively inhibited the replication of influenza viruses but had no inhibitory effect on other RNA viruses: Sendai, RS, vesicular stomatitis and western equine encephalitis viruses.
6-巯基嘌呤(6MP)、6-硫代肌苷、6-甲硫基肌苷和6-乙硫基肌苷对某些RNA病毒的抗病毒活性。所有化合物均能广泛抑制流感病毒的复制,但对其他RNA病毒:仙台病毒、呼吸道合胞病毒(RS)、水泡性口炎病毒和西部马脑炎病毒没有抑制作用。