Cheng Xuemin, Li Maolin, Zhou Jialing, Ma Hui, Hao Qun
Appl Opt. 2017 Sep 1;56(25):7067-7074. doi: 10.1364/AO.56.007067.
We previously developed a Mueller matrix microscope by combining a dual-rotating-retarder device with a commercial microscope, which holds promise for pathologic diagnosis applications. In practical applications, the signals to be measured are sensitive to systematic errors, and the measurement accuracy and the instrument calibration affect the capacity to characterize the data. In conventional calibration, the initial positions of the rotating devices are constrained, causing calibration instability. To improve the calibration, we examine the mathematical model of the calibration process using previous studies, and derive a calibration algorithm with reduced error magnification. Our experimental results show the proposed algorithm improves calibration accuracy, and provides more robust results.
我们之前通过将双旋转延迟器装置与商用显微镜相结合，开发出了一台穆勒矩阵显微镜，这对于病理诊断应用具有前景。在实际应用中，待测量的信号对系统误差敏感，测量精度和仪器校准会影响数据表征能力。在传统校准中，旋转装置的初始位置受到限制，导致校准不稳定。为了改进校准，我们利用先前的研究来研究校准过程的数学模型，并推导了一种误差放大率降低的校准算法。我们的实验结果表明，所提出的算法提高了校准精度，并提供了更可靠的结果。
