Department of Research, Cancer Registry of Norway, N-0304 Oslo, Norway.
Department of Global Public Health and Primary Care, University of Bergen, N-5020 Bergen, Norway.
Occup Med (Lond). 2017 Oct 1;67(7):569-573. doi: 10.1093/occmed/kqx110.
Excess skin cancer mortality and incidence have been reported among both land-based and offshore petroleum workers. The association between skin cancer and ultraviolet radiation (UVR) exposure has not been examined in these workers, although they have long off-duty periods and high average income that may allow travelling to sunny destinations. In addition, they have access to solariums free of charge on many accommodation platforms.
To prospectively examine risk of incident cutaneous melanoma (CM) and non-melanoma skin cancer (NMSC), according to sun-tanning habits with adjustment for aromatic hydrocarbon exposure.
A cohort of men employed offshore from 1965 to 1999 was linked through the Cancer Registry of Norway 1999-2012. Cox regression adapted to a stratified case-cohort design was used to estimate hazard ratios with 95% confidence intervals.
The cohort included 24917 men. During 13.5 years of follow-up, 112 CMs and 70 NMSCs occurred. A positive dose-response relationship was seen between sunburn frequency and risk of CM (Ptrend < 0.05) and NMSC (Ptrend < 0.01). Solarium use both before and after age 20 was related to increased risk of NMSC. Sunscreen use was associated with increased risk of NMSC (Ptrend < 0.001).
UVR exposure seems to be a significant contributor to the elevated risk of skin cancer observed in North Sea offshore workers. The positive association between solarium use and NMSC risk adds to the growing body of literature on artificial UV devices as carcinogenic.
陆地和海上石油工人的皮肤癌死亡率和发病率都有所增加。尽管这些工人有很长的休息时间和较高的平均收入，可以去阳光充足的地方旅游，但他们的皮肤癌与紫外线（UVR）暴露之间的关系尚未在这些工人中进行过研究。此外，他们可以在许多住宿平台上免费使用日光浴室。
前瞻性研究根据晒黑习惯，调整芳烃暴露，分析皮肤黑色素瘤（CM）和非黑色素瘤皮肤癌（NMSC）的发病风险。
通过挪威癌症登记处 1999-2012 年，对 1965 年至 1999 年期间从事海上工作的男性进行了队列研究。使用 Cox 回归调整分层病例-队列设计来估计风险比和 95%置信区间。
该队列包括 24917 名男性。在 13.5 年的随访期间，发生了 112 例 CM 和 70 例 NMSC。晒伤频率与 CM（Ptrend <0.05）和 NMSC（Ptrend <0.01）风险之间呈正剂量反应关系。20 岁前后使用日光浴室与 NMSC 风险增加有关。防晒霜的使用与 NMSC 风险增加相关（Ptrend <0.001）。
UVR 暴露似乎是北海海上工人皮肤癌风险增加的一个重要因素。日光浴室使用与 NMSC 风险之间的正相关关系增加了人工 UV 设备致癌的文献数量。
