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[Synthesis and antiparasitic activity of arylproprenones in the nitro-5-imidazole series].

作者信息

Ouattara L, Debaert M, Cavier R

机构信息

Laboratoire de Chimie Thérapeutique et Chimique Organique, Faculté de Pharmacie D'Abidjan, Côte D'Ivoire.

出版信息

Farmaco Sci. 1988 Apr;43(4):389-93.

PMID:2904887
Abstract

The synthesis of new arylpropenones derived from 1-methyl-5-nitro imidazole is described. The investigation of some antiprotozoal properties has shown that compounds with the groups 4-hydroxyphenyl, 4-chlorophenyl or thiophenyl have trichomonacidal activity similar to that of metronidazole.

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