Hossain A
Department of Pathology (32), College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Int J Gynaecol Obstet. 1988 Dec;27(3):377-80. doi: 10.1016/0020-7292(88)90116-6.
The serology of various infections often caused by Chlamydia trachomatis including complications such as pelvic inflammatory disease (PID) and infertility was investigated comprehensively among diverse patient groups in a developing country using initially an indirect immunofluorescent antibody test (IFA). Any positives detected were further examined by a micro-immunofluorescence (MIF) method for the presence of type specific anti-chlamydial IgG/IgM antibodies. Conventional cell culture was carried out concurrently to compare culture results with serologic results. Among 416 patients (107 males and 309 females) C. trachomatis D-K antibodies to IgG were identified in 87 (20.9%) and to type specific IgM were identified in 11(2.6%) patients. Cell culture identified C. trachomatis in 60 patients (14.4%). C. trachomatis IgG antibodies were detectable in 6.4% of chlamydia culture negative patients.
在一个发展中国家，针对不同患者群体，最初采用间接免疫荧光抗体试验（IFA），全面调查了由沙眼衣原体引起的各种感染的血清学情况，这些感染常伴有盆腔炎（PID）和不孕症等并发症。对检测出的任何阳性结果，进一步采用微量免疫荧光（MIF）方法检查是否存在型特异性抗衣原体IgG/IgM抗体。同时进行传统细胞培养，以比较培养结果和血清学结果。在416例患者（107例男性和309例女性）中，87例（20.9%）患者检测出沙眼衣原体D-K型IgG抗体，11例（2.6%）患者检测出型特异性IgM抗体。细胞培养在60例患者（14.4%）中鉴定出沙眼衣原体。在衣原体培养阴性的患者中，6.4%可检测到沙眼衣原体IgG抗体。
