Rojanasakul A, Chailurkit L, Sirimongkolkasem R, Chaturachinda K
Department of Obstetrics and Gynecology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Int J Gynaecol Obstet. 1988 Dec;27(3):401-6. doi: 10.1016/0020-7292(88)90121-x.
A study to determine serum lipids and lipoproteins in 54 women with polycystic ovarian disease (PCOD) who had varying body mass index (BMI) compared to the normal regular menstruating women was carried out. All patients had similar hormonal profiles of PCOD and differed from the control group. The significant observations were high level of triglyceride and low percentage of alpha lipoprotein in obese PCOD. The BMI was positively correlated with serum triglyceride level, beta and prebeta lipoproteins but inversely correlated with high density lipoprotein (HDL) cholesterol, the low density lipoprotein (LDL) cholesterol/HDL cholesterol ratio and alpha lipoprotein. No significant correlation between lipids, lipoproteins and testosterone levels was observed. It appeared that the alteration of serum lipids and lipoproteins in PCOD is due to the effect of obesity.
一项关于54名多囊卵巢疾病（PCOD）女性血清脂质和脂蛋白的研究开展了，这些女性具有不同的体重指数（BMI），并与正常规律月经的女性进行比较。所有患者的PCOD激素谱相似，且与对照组不同。重要观察结果是肥胖型PCOD患者甘油三酯水平高，α脂蛋白百分比低。BMI与血清甘油三酯水平、β和前β脂蛋白呈正相关，但与高密度脂蛋白（HDL）胆固醇、低密度脂蛋白（LDL）胆固醇/HDL胆固醇比值和α脂蛋白呈负相关。未观察到脂质、脂蛋白与睾酮水平之间存在显著相关性。看来PCOD患者血清脂质和脂蛋白的改变是肥胖所致。
