Celik T
Bratisl Lek Listy. 2017;118(8):495-498. doi: 10.4149/BLL_2017_095.
To evaluate the neutrophil-to-lymphocyte ratio (NLR) levels to predict the severity of inflammation in thyroid ophthalmopathy (TO).
Fifty-six patients with TO and 40 healthy subjects were included in this study. TO patients were divided into two groups according to clinical activity score (CAS). Group 1 included 24 active TO patients and Group 2 included 32 inactive TO patients. The thyroid status, white blood cell (WBC), neutrophil, and lymphocyte counts were performed. NLR was calculated by dividing the neutrophil count by the lymphocyte count.
The mean age was 53.6 ± 5.4 in active TO group, 54.2 ± 5.6 in inactive TO group, and 52.7 ± 5.2 in the control group. The WBC, neutrophil, lymphocyte and NLR levels were higher in patients with TO than in the control group (p < 0.05). A significant difference in NLR was found between the inactive and active TO groups (p < 0.05).
NLR values were found to be higher in patients with TO than in controls. NLRvalues were also found higher in active TO patients than in inactive TO patients (Tab. 3, Ref. 26).
评估中性粒细胞与淋巴细胞比值（NLR）水平，以预测甲状腺眼病（TO）的炎症严重程度。
本研究纳入了56例TO患者和40名健康受试者。TO患者根据临床活动评分（CAS）分为两组。第1组包括24例活动期TO患者，第2组包括32例非活动期TO患者。检测甲状腺状态、白细胞（WBC）、中性粒细胞和淋巴细胞计数。NLR通过中性粒细胞计数除以淋巴细胞计数计算得出。
活动期TO组的平均年龄为53.6±5.4岁，非活动期TO组为54.2±5.6岁，对照组为52.7±5.2岁。TO患者的WBC、中性粒细胞、淋巴细胞和NLR水平高于对照组（p<0.05）。非活动期和活动期TO组之间的NLR存在显著差异（p<0.05）。
发现TO患者的NLR值高于对照组。活动期TO患者的NLR值也高于非活动期TO患者（表3，参考文献26）。
